Article
Psychiatry
Stephanie Allan, Sara Beedie, Hamish J. McLeod, John Farhall, John Gleeson, Simon Bradstreet, Emma Morton, Imogen Bell, Alison Wilson-Kay, Helen Whitehill, Claire Matrunola, David Thomson, Andrea Clark, Andrew Gumley
Summary: Digital self-management tools blended with clinical triage and peer support have the potential to improve access to early warning signs (EWS) based relapse prevention in schizophrenia care. The implementation of digital interventions in psychosis can be poor, and there is a need to understand implementation from the perspectives of patients and carers.
Review
Psychiatry
Felipe Ponce-Correa, Alejandra Caqueo-Urizar, Raul Berrios, Carolang Escobar-Soler
Summary: Schizophrenia is a chronic disorder with diverse ways of measuring recovery. Recovery can be assessed from a clinical perspective or from a patient-focused viewpoint. This meta-analysis examined the relationship between subjective recovery and clinical components of recovery in patients with schizophrenia spectrum disorders. The results showed weak and inverse associations between indicators of personal recovery and remission, but a moderate relationship between functionality and personal recovery.
PSYCHIATRY RESEARCH
(2023)
Article
Medicine, General & Internal
Alejandra Caqueo-Urizar, Felipe Ponce-Correa, Carla Semir-Gonzalez, Alfonso Urzua
Summary: Premorbid adjustment refers to psychosocial functioning in areas such as education, occupation, and relationships prior to the onset of characteristic positive symptoms in schizophrenia. This study found that premorbid adjustment is significantly correlated with recovery indicators and that patients with better premorbid adjustment show better outcomes in terms of subjective recovery and stigma resistance. These findings highlight the importance of psychosocial functioning prior to psychosis in shaping patients' subjective experiences, understanding of the disorder, and recovery process.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Carmen Concerto, Alessandro Rodolico, Ludovico Mineo, Alessia Ciancio, Leonardo Marano, Carla Benedicta Romano, Elisa Vita Scavo, Riccardo Spigarelli, Laura Fusar-Poli, Rosaria Furnari, Antonino Petralia, Maria Salvina Signorelli
Summary: This study aims to understand the correlation between personal recovery from schizophrenia and factors such as mentalization, disability, quality of life, and antipsychotic side effects. The findings revealed that there is a positive association between recovery assessment scale (RAS) scores and multidimensional mentalizing questionnaire (MMQ) scores, especially in good mentalizing subdomains. Insight orientation scale (IOS) scores also showed a positive correlation with RAS and MMQ scores. On the other hand, poor mentalizing abilities were negatively correlated with WHO Disability Assessment Schedule (WHO-DAS) 2.0 scores. While antipsychotic side effects influenced functioning, they did not impact perceived recovery. These findings could contribute to tailored interventions for facilitating the recovery process.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Psychiatry
Julien Dubreucq, Franck Gabayet, Ophelia Godin, Myrtille Andre, Bruno Aouizerate, Delphine Capdevielle, Isabelle Chereau, Julie Clauss-Kobayashi, Nathalie Coulon, Thierry D'Amato, Jean-Michel Dorey, Caroline Dubertret, Megane Faraldo, Hakim Laouamri, Sylvain Leigner, Christophe Lancon, Marion Leboyer, Pierre-Michel Llorca, Jasmina Mallet, David Misdrahi, Christine Passerieux, Romain Rey, Baptiste Pignon, Benoit Schorr, Mathieu Urbach, Franck Schurhoff, Andrei Szoke, Guillaume Fond, Fabrice Berna
Summary: Recovery is a multidimensional process aiming at living a meaningful life beyond mental illness, and this study found that clinical recovery and personal recovery predict each other over time. Psychosocial treatment should target subjective aspects such as personal recovery and depression in addition to clinical recovery to achieve full recovery.
SCHIZOPHRENIA BULLETIN
(2022)
Review
Psychiatry
Helene Gjervig Hansen, Helene Speyer, Marie Starzer, Nikolai Albert, Carsten Hjorthoj, Lene Falgaard Eplov, Merete Nordentoft
Summary: This study conducted a comprehensive analysis of previous research on individuals with schizophrenia and found a clinical recovery rate of approximately 21%. The study also found that the recovery rate was not significantly influenced by various factors, and there was no significant difference in recovery between early intervention services and other interventions. New initiatives are needed to improve the rate of recovery.
SCHIZOPHRENIA BULLETIN
(2023)
Article
Biochemistry & Molecular Biology
Maxwell L. Elliott, Daniel W. Belsky, Annchen R. Knodt, David Ireland, Tracy R. Melzer, Richie Poulton, Sandhya Ramrakha, Avshalom Caspi, Terrie E. Moffitt, Ahmad R. Hariri
Summary: BrainAGE, a measure of the difference between predicted age from brain-imaging data and chronological age, has been proposed as a biomarker for age-related brain deterioration. Studies suggest that individuals with older brainAGEs may be more susceptible to Alzheimer's, dementia, and mortality, but further research is needed to validate its effectiveness.
MOLECULAR PSYCHIATRY
(2021)
Article
Psychiatry
Stynke Castelein, Marieke E. Timmerman, Mark van der Gaag, Ellen Visser
Summary: Recovery in schizophrenia is a complex and multi-faceted process involving clinical, societal, and personal factors. This study used a mixture latent Markov model to analyze data from schizophrenia patients in the Northern Netherlands over 11 years, revealing different states of recovery and transition rates between states. Findings showed that patients with shorter illness duration, less severe symptoms, and female gender were more likely to achieve better recovery outcomes.
BRITISH JOURNAL OF PSYCHIATRY
(2021)
Article
Multidisciplinary Sciences
Alvin Saputra, A. A. A. A. Kusumawardhani, Sylvia Detri Elvira, Tjhin Wiguna
Summary: This study aimed to explore the definitions of mental health recovery among individuals with schizophrenia spectrum disorders in Indonesia, develop a recovery scale tailored to the Indonesian cultural context, and evaluate its content validity.
Article
Psychiatry
Gael Galliot, Raquel Sanchez-Rodriguez, Alice Belloc, Hugo Phulpin, Adrien Icher, Philippe Birmes, Karine Faure, Tudi Goze
Summary: Good clinical insight has limited impact on subjective recovery in individuals with psychotic disorders, with only unawareness of current symptoms significantly associated with recovery. This study emphasizes the importance of considering patients' meaning-making process of morbid experiences in order to facilitate self-directed and medically-supported recovery.
PSYCHIATRY RESEARCH
(2022)
Article
Multidisciplinary Sciences
Z. T. Zhao, Z. Wang, C. Feng, S. Chen, L. Cao
Summary: The paper explores the combination of ERL with angular-dispersion induced microbunching technique to generate fully coherent radiation pulses with high average brightness and tunable pulse length. Start-to-end simulations based on a low energy ERL show promising results in generating coherent EUV radiation pulses with high brightness and power using the proposed technique. Further discussions are made on extending the proposed scheme to shorter wavelength based on an ERL complex.
SCIENTIFIC REPORTS
(2021)
Article
Psychiatry
B. Esther Sportel, Hettie Aardema, Nynke Boonstra, Johannes Arends, Bridey Rudd, Margot J. Metz, Stynke Castelein, Gerdina H. M. Pijnenborg
Summary: This study evaluated the psychometric properties of the Individual Recovery Outcomes Counter (I.ROC) in a Dutch population with schizophrenia spectrum disorder (SSD). The results showed that the I.ROC has good internal consistency and test-retest reliability, with moderate and small correlations with other assessment tools. The study suggests that the I.ROC is a valid and reliable instrument for assessing recovery in patients with SSD.
Article
Psychiatry
Katrin Bahlinger, Tania M. Lincoln, Annika Clamor
Summary: The study found that individuals with psychosis have delayed subjective stress recovery but no deficits in autonomic recovery, suggesting that prolonged stress responses may not contribute to heightened stress levels as expected. Improvements in resting-state HRV and emotion regulation may support autonomic recovery.
SCHIZOPHRENIA BULLETIN
(2022)
Article
Psychiatry
Sri Padma Sari, Murti Agustin, Diyan Yuli Wijayanti, Widodo Sarjana, Umi Afrikhah, Kwisoon Choe
Summary: The study found that depression moderates the relationship between hope and recovery, and hope mediates the relationship between depression and recovery in individuals with schizophrenia. Mental health professionals should focus on instilling hope and reducing depression to improve the recovery of individuals with schizophrenia, and should actively develop and evaluate programs to instill hope, particularly in community-based and in-patient mental health settings.
FRONTIERS IN PSYCHIATRY
(2021)
Review
Clinical Neurology
Toshiaki Onitsuka, Yoji Hirano, Takanobu Nakazawa, Kayo Ichihashi, Kenichiro Miura, Ken Inada, Ryo Mitoma, Norio Yasui-Furukori, Ryota Hashimoto
Summary: Schizophrenia was initially defined as early-onset dementia, but recent studies have shown that early intervention can lead to improvement in social functioning. Current research focuses on pathophysiological hypotheses and neuroimaging studies to identify biological differences in schizophrenia.
PSYCHIATRY AND CLINICAL NEUROSCIENCES
(2022)
