The importance of a validated standard methodology to define in vitro toxicity of nano-TiO2

Analysis of currently available data for characterising the risk of engineered nanomaterials to the environment and human health — Lessons learned from four case studies

(2011) Karin Aschberger et al.   ENVIRONMENT INTERNATIONAL

Comparative in vitro cytotoxicity study of carbon nanotubes and titania nanostructures on human lung epithelial cells

(2011) S. Wadhwa et al.   JOURNAL OF HAZARDOUS MATERIALS

Biological impacts of TiO2 on human lung cell lines A549 and H1299: particle size distribution effects

(2011) Roslyn Tedja et al.   JOURNAL OF NANOPARTICLE RESEARCH

Validation of an LDH assay for assessing nanoparticle toxicity

(2011) Xianglu Han et al.   TOXICOLOGY

Analysis for the potential of polystyrene and TiO2 nanoparticles to induce skin irritation, phototoxicity, and sensitization

(2011) Yoon-Hee Park et al.   TOXICOLOGY IN VITRO

Limitation of the MTT and XTT assays for measuring cell viability due to superoxide formation induced by nano-scale TiO2

(2011) Shuguang Wang et al.   TOXICOLOGY IN VITRO

Ecotoxicity of nanosized TiO2. Review of in vivo data

(2010) Anja Menard et al.   ENVIRONMENTAL POLLUTION

Cellular responses by stable and uniform ultrafine titanium dioxide particles in culture-medium dispersions when secondary particle size was 100nm or less

(2010) Masanori Horie et al.   TOXICOLOGY IN VITRO

Titanium dioxide nanoparticles cause apoptosis in BEAS-2B cells through the caspase 8/t-Bid-independent mitochondrial pathway

(2010) Yongli Shi et al.   TOXICOLOGY LETTERS

Involvement of JNK and P53 activation in G2/M cell cycle arrest and apoptosis induced by titanium dioxide nanoparticles in neuron cells

(2010) Jie Wu et al.   TOXICOLOGY LETTERS

Intracellular distribution, geno- and cytotoxic effects of nanosized titanium dioxide particles in the anatase crystal phase on human nasal mucosa cells

(2010) Stephan Hackenberg et al.   TOXICOLOGY LETTERS

Genotoxic effects of nanosized and fine TiO2

(2009) GCM Falck et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Physico-chemical characterization in the light of toxicological effects

(2009) Tobias Meißner et al.   INHALATION TOXICOLOGY

Comparative study of the cytotoxic and genotoxic effects of titanium oxide and aluminium oxide nanoparticles in Chinese hamster ovary (CHO-K1) cells

(2009) A.L. Di Virgilio et al.   JOURNAL OF HAZARDOUS MATERIALS

The status ofin vitrotoxicity studies in the risk assessment of nanomaterials

(2009) Margriet VDZ Park et al.   Nanomedicine

Genotoxic responses to titanium dioxide nanoparticles and fullerene in gpt delta transgenic MEF cells

(2009) An Xu et al.   Particle and Fibre Toxicology

Are In Vitro Tests Suitable for Regulatory Use?

(2009) Thomas Hartung et al.   TOXICOLOGICAL SCIENCES

Engineered nanomaterials cause cytotoxicity and activation on mouse antigen presenting cells

(2009) J. Palomäki et al.   TOXICOLOGY

Oxidative stress and apoptosis induced by nanosized titanium dioxide in PC12 cells

(2009) Shichang Liu et al.   TOXICOLOGY

Disturbed mitotic progression and genome segregation are involved in cell transformation mediated by nano-TiO2 long-term exposure

(2009) Shing Huang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inhibitor of differentiation 1 (Id1) expression attenuates the degree of TiO2-induced cytotoxicity in H1299 non-small cell lung cancer cells

(2009) Young Sook Lee et al.   TOXICOLOGY LETTERS

Effects of ultrafine TiO2 particles on gene expression profile in human keratinocytes without illumination: Involvement of extracellular matrix and cell adhesion

(2009) Katsuhide Fujita et al.   TOXICOLOGY LETTERS

Cytotoxicity of Titanium Dioxide Nanoparticles in Mouse Fibroblast Cells

(2008) Cheng-Yu Jin et al.   CHEMICAL RESEARCH IN TOXICOLOGY

An in vitro investigation of the differential cytotoxic responses of human and rat lung epithelial cell lines using TiO2 nanoparticles

(2008) Christie M. Sayes et al.   International Journal of Nanotechnology

Crystal structure mediates mode of cell death in TiO2 nanotoxicity

(2008) Laura K. Braydich-Stolle et al.   JOURNAL OF NANOPARTICLE RESEARCH

Bio-effects of Nano-TiO2 on DNA and cellular ultrastructure with different polymorph and size

(2008) Rong R. Zhu et al.   Materials Science & Engineering C-Materials for Biological Applications

How Meaningful are the Results of Nanotoxicity Studies in the Absence of Adequate Material Characterization?

(2008) David B. Warheit   TOXICOLOGICAL SCIENCES

In vitro investigation of oxide nanoparticle and carbon nanotube toxicity and intracellular accumulation in A549 human pneumocytes

(2008) A. Simon-Deckers et al.   TOXICOLOGY

The effects of nanoparticles on mouse testis Leydig cells in vitro

(2008) Tomoko Komatsu et al.   TOXICOLOGY IN VITRO

Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells

(2008) Eun-Jung Park et al.   TOXICOLOGY LETTERS