Nematode modulation of inflammatory bowel disease

CD8+CD205+ Splenic Dendritic Cells Are Specialized to Induce Foxp3+ Regulatory T Cells

(2014) S. Yamazaki et al.   JOURNAL OF IMMUNOLOGY

IL-33, a Potent Inducer of Adaptive Immunity to Intestinal Nematodes

(2014) N. E. Humphreys et al.   JOURNAL OF IMMUNOLOGY

Expansion of Foxp3+ Regulatory T Cells in Mice Infected with the Filarial Parasite Brugia malayi

(2014) H. J. McSorley et al.   JOURNAL OF IMMUNOLOGY

Colonization with Heligmosomoides polygyrus Suppresses Mucosal IL-17 Production

(2014) D. E. Elliott et al.   JOURNAL OF IMMUNOLOGY

A Helminth Immunomodulator Reduces Allergic and Inflammatory Responses by Induction of IL-10-Producing Macrophages

(2014) C. Schnoeller et al.   JOURNAL OF IMMUNOLOGY

Dietary Intake and Risk of Developing Inflammatory Bowel Disease: A Systematic Review of the Literature

(2011) Jason K Hou et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Protective Effect of the Recombinant 53-kDa Protein of Trichinella spiralis on Experimental Colitis in Mice

(2011) Linlin Du et al.   DIGESTIVE DISEASES AND SCIENCES

Interleukin-10 Signaling in Regulatory T Cells Is Required for Suppression of Th17 Cell-Mediated Inflammation

(2011) Ashutosh Chaudhry et al.   IMMUNITY

Hookworm products ameliorate dextran sodium sulfate-induced colitis in BALB/c mice

(2011) Guilherme Grossi Lopes Cançado et al.   INFLAMMATORY BOWEL DISEASES

Inhibition of colitis by IL-25 associates with induction of alternatively activated macrophages

(2011) Angelamaria Rizzo et al.   INFLAMMATORY BOWEL DISEASES

The phenotype and function of naturally existing regulatory dendritic cells in nematode-infected mice

(2011) Zhaotao Li et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Preexisting helminth infection induces inhibition of innate pulmonary anti-tuberculosis defense by engaging the IL-4 receptor pathway

(2011) Julius A. Potian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chronic Helminth Infection Promotes Immune Regulation In Vivo through Dominance of CD11cloCD103- Dendritic Cells

(2011) K. A. Smith et al.   JOURNAL OF IMMUNOLOGY

SHIP-deficient, alternatively activated macrophages protect mice during DSS-induced colitis

(2011) Shelley B. Weisser et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A role for interleukin-33 in TH2-polarized intestinal inflammation?

(2011) J B Seidelin et al.   Mucosal Immunology

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

Effect of Hookworm Infection on Wheat Challenge in Celiac Disease – A Randomised Double-Blinded Placebo Controlled Trial

(2011) A. James Daveson et al.   PLoS One

Symptoms after Ingestion of Pig Whipworm Trichuris suis Eggs in a Randomized Placebo-Controlled Double-Blind Clinical Trial

(2011) Peter Bager et al.   PLoS One

Management of gut inflammation through the manipulation of intestinal dendritic cells and macrophages?

(2011) Liat Bar-On et al.   SEMINARS IN IMMUNOLOGY

A Helminth Immunomodulator Exploits Host Signaling Events to Regulate Cytokine Production in Macrophages

(2011) Christian Klotz et al.   PLoS Pathogens

Induction and Activation of Adaptive Immune Populations During Acute and Chronic Phases of a Murine Model of Experimental Colitis

(2010) Lindsay J. Hall et al.   DIGESTIVE DISEASES AND SCIENCES

In Vitro-Derived Alternatively Activated Macrophages Reduce Colonic Inflammation in Mice

(2010) Meaghan M. Hunter et al.   GASTROENTEROLOGY

Colitis and Intestinal Inflammation in IL10−/− Mice Results From IL-13Rα2–Mediated Attenuation of IL-13 Activity

(2010) Mark S. Wilson et al.   GASTROENTEROLOGY

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

(2010) John R. Grainger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Heligmosomoides polygyrus Infection Can Inhibit Colitis through Direct Interaction with Innate Immunity

(2010) L. Hang et al.   JOURNAL OF IMMUNOLOGY

At Homeostasis Filarial Infections Have Expanded Adaptive T Regulatory but Not Classical Th2 Cells

(2010) S. Metenou et al.   JOURNAL OF IMMUNOLOGY

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Programming dendritic cells to induce TH2 and tolerogenic responses

(2010) Bali Pulendran et al.   NATURE IMMUNOLOGY

IL-35-mediated induction of a potent regulatory T cell population

(2010) Lauren W Collison et al.   NATURE IMMUNOLOGY

Amelioration of intestinal colitis by macrophage migration inhibitory factor isolated from intestinal parasites through Toll-like receptor 2

(2010) M. K. CHO et al.   PARASITE IMMUNOLOGY

Systemically dispersed innate IL-13-expressing cells in type 2 immunity

(2010) A. E. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-22+ CD4+ T Cells Are Associated with Therapeutic Trichuris trichiura Infection in an Ulcerative Colitis Patient

(2010) M. J. Broadhurst et al.   Science Translational Medicine

IL-17 and IL-22: siblings, not twins

(2010) Stefanie Eyerich et al.   TRENDS IN IMMUNOLOGY

Regulatory Lymphocytes and Intestinal Inflammation

(2009) Ana Izcue et al.   Annual Review of Immunology

Gastrointestinal nematode infection interferes with experimental allergic airway inflammation but not atopic dermatitis

(2009) S. Hartmann et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Establishment of nematode infection despite increased Th2 responses and immunopathology after selective depletion of Foxp3+cells

(2009) Sebastian Rausch et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Concurrent infection withHeligmosomoides polygyrussuppresses anti-Plasmodium yoeliiprotection partially by induction of CD4+CD25+Foxp3+Treg in mice

(2009) Kohhei Tetsutani et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Role of T cell TGF-β signaling in intestinal cytokine responses and helminthic immune modulation

(2009) M. Nedim Ince et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-25 Inhibits Interleukin-12 Production and Th1 Cell-Driven Inflammation in the Gut

(2009) Roberta Caruso et al.   GASTROENTEROLOGY

Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites

(2009) Steven A. Saenz et al.   IMMUNOLOGICAL REVIEWS

Dynamics of CD11c+ dendritic cell subsets in lymph nodes draining the site of intestinal nematode infection

(2009) Adam Balic et al.   IMMUNOLOGY LETTERS

Intestinal epithelial cell secretion of RELM-β protects against gastrointestinal worm infection

(2009) De'Broski R. Herbert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis

(2009) Betsy C. Taylor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions

(2009) Matteo Fumagalli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Rapid Dendritic Cell Mobilization to the Large Intestinal Epithelium Is Associated with Resistance to Trichuris muris Infection

(2009) S. M. Cruickshank et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells: A Role in the Control of Helminth-Driven Intestinal Pathology and Worm Survival

(2009) R. D'Elia et al.   JOURNAL OF IMMUNOLOGY

Alternatively Activated Macrophages Elicited by Helminth Infection Can Be Reprogrammed to Enable Microbial Killing

(2009) K. J. Mylonas et al.   JOURNAL OF IMMUNOLOGY

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

(2009) Masako Murai et al.   NATURE IMMUNOLOGY

Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function

(2009) J. C. Massacand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Necator americanus Infection: A Possible Cause of Altered Dendritic Cell Differentiation and Eosinophil Profile in Chronically Infected Individuals

(2009) Ricardo T. Fujiwara et al.   PLoS Neglected Tropical Diseases

Regulatory T Cell Expansion in HTLV-1 and Strongyloidiasis Co-infection Is Associated with Reduced IL-5 Responses to Strongyloides stercoralis Antigen

(2009) Martin Montes et al.   PLoS Neglected Tropical Diseases

The Hookworm Tissue Inhibitor of Metalloproteases (Ac-TMP-1) Modifies Dendritic Cell Function and Induces Generation of CD4 and CD8 Suppressor T Cells

(2009) Carmen Cuéllar et al.   PLoS Neglected Tropical Diseases

Helminth antigen-based strategy to ameliorate inflammation in an experimental model of colitis

(2008) Y. Motomura et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Ascaris lumbricoides-induced suppression of total and specific IgE responses in atopic subjects is interleukin 10-independent and associated with an increase of CD25+ cells

(2008) Giovanni Matera et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

Anti-Inflammatory Mechanisms of Enteric Heligmosomoides polygyrus Infection against Trinitrobenzene Sulfonic Acid-Induced Colitis in a Murine Model

(2008) T. L. Sutton et al.   INFECTION AND IMMUNITY

Functional Analysis of Effector and Regulatory T Cells in a Parasitic Nematode Infection

(2008) S. Rausch et al.   INFECTION AND IMMUNITY

Hookworm-Induced Persistent Changes to the Immunological Environment of the Lung

(2008) J. J. Reece et al.   INFECTION AND IMMUNITY

Resistin-like molecule β regulates intestinal mucous secretion and curtails TNBS-induced colitis in mice

(2008) Rim Belharbi Krimi et al.   INFLAMMATORY BOWEL DISEASES

Therapeutic potential of helminth soluble proteins in TNBS-induced colitis in mice

(2008) Nathalie E. Ruyssers et al.   INFLAMMATORY BOWEL DISEASES

Alarming dendritic cells for Th2 induction

(2008) Andrew S. MacDonald et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dynamics of lung macrophage activation in response to helminth infection

(2008) Mark C. Siracusa et al.   JOURNAL OF LEUKOCYTE BIOLOGY

TGF-β1 and Smad7 in the regulation of IBD

(2008) G Monteleone et al.   Mucosal Immunology

Role of mucosal dendritic cells in inflammatory bowel disease

(2008) Jan Hendrik Niess   WORLD JOURNAL OF GASTROENTEROLOGY