Reconstructing the pipeline by introducing multiplexed multiple reaction monitoring mass spectrometry for cancer biomarker verification: An NCI-CPTC initiative perspective

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

The evolving role of mass spectrometry in cancer biomarker discovery

(2010) Pei Wang et al.   CANCER BIOLOGY & THERAPY

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Workflow Comparison for Label-Free, Quantitative Secretome Proteomics for Cancer Biomarker Discovery: Method Evaluation, Differential Analysis, and Verification in Serum

(2010) Sander R. Piersma et al.   JOURNAL OF PROTEOME RESEARCH

Towards the development of an immuno MALDI (iMALDI) mass spectrometry assay for the diagnosis of hypertension

(2010) Jennifer D. Reid et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

International network of cancer genome projects

(2010) Thomas J. Hudson (Chairperson) et al.   NATURE

The Path to Personalized Medicine

(2010) Margaret A. Hamburg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Enabling individualized therapy through nanotechnology

(2010) Jason H. Sakamoto et al.   PHARMACOLOGICAL RESEARCH

Absolute Quantification of Phosphorylation on the Kinase Activation Loop of Cellular Focal Adhesion Kinase by Stable Isotope Dilution Liquid Chromatography/Mass Spectrometry

(2009) Eugene Ciccimaro et al.   ANALYTICAL CHEMISTRY

Approaches to biomarkers in human colorectal cancer: looking back, to go forward

(2009) Rod K Nibbe et al.   Biomarkers in Medicine

Identification of Candidate Biomarkers of Therapeutic Response to Docetaxel by Proteomic Profiling

(2009) L. Zhao et al.   CANCER RESEARCH

Protein-Based Multiplex Assays: Mock Presubmissions to the US Food and Drug Administration

(2009) F. E. Regnier et al.   CLINICAL CHEMISTRY

Integration of Proteomic-Based Tools for Improved Biomarkers of Myocardial Injury

(2009) R. E. Gerszten et al.   CLINICAL CHEMISTRY

Analytical Validation of Protein-Based Multiplex Assays: A Workshop Report by the NCI-FDA Interagency Oncology Task Force on Molecular Diagnostics

(2009) H. Rodriguez et al.   CLINICAL CHEMISTRY

The Bottleneck in the Cancer Biomarker Pipeline and Protein Quantification through Mass Spectrometry-Based Approaches: Current Strategies for Candidate Verification

(2009) S. Makawita et al.   CLINICAL CHEMISTRY

The Clinical Plasma Proteome: A Survey of Clinical Assays for Proteins in Plasma and Serum

(2009) N. L. Anderson   CLINICAL CHEMISTRY

Sweetening the Pot: Adding Glycosylation to the Biomarker Discovery Equation

(2009) P. M. Drake et al.   CLINICAL CHEMISTRY

Developing Multiplexed Assays for Troponin I and Interleukin-33 in Plasma by Peptide Immunoaffinity Enrichment and Targeted Mass Spectrometry

(2009) E. Kuhn et al.   CLINICAL CHEMISTRY

Mass spectrometry based proteomics profiling as diagnostic tool in oncology: current status and future perspective

(2009) Peter Findeisen et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Multiplexed Cell Signaling Analysis of Metastatic and Nonmetastatic Colorectal Cancer Reveals COX2-EGFR Signaling Activation as a Potential Prognostic Pathway Biomarker

(2009) Mariaelena Pierobon et al.   Clinical Colorectal Cancer

Multiplex immune serum biomarker profiling in sarcoidosis and systemic sclerosis

(2009) P. Beirne et al.   EUROPEAN RESPIRATORY JOURNAL

The fundamental flaws of immunoassays and potential solutions using tandem mass spectrometry

(2009) Andrew N. Hoofnagle et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Proteomic analysis of lymphoid and haematopoietic neoplasms: There's more than biomarker discovery

(2009) Alberto Zamò et al.   Journal of Proteomics

Interlaboratory Study Characterizing a Yeast Performance Standard for Benchmarking LC-MS Platform Performance

(2009) Amanda G. Paulovich et al.   MOLECULAR & CELLULAR PROTEOMICS

SISCAPA Peptide Enrichment on Magnetic Beads Using an In-line Bead Trap Device

(2009) N. Leigh Anderson et al.   MOLECULAR & CELLULAR PROTEOMICS

Global Effects of Kinase Inhibitors on Signaling Networks Revealed by Quantitative Phosphoproteomics

(2009) Cuiping Pan et al.   MOLECULAR & CELLULAR PROTEOMICS

Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma

(2009) Terri A Addona et al.   NATURE BIOTECHNOLOGY

A HUPO test sample study reveals common problems in mass spectrometry–based proteomics

(2009) Alexander W Bell et al.   NATURE METHODS

The potential of optical proteomic technologies to individualize prognosis and guide rational treatment for cancer patients

(2009) Muireann T. Kelleher et al.   Targeted Oncology

Translating genomics into clinical practice: Applications in lung cancer

(2009) Aubrey Jolly Graham et al.   Current Oncology Reports

Quantification of Thyroglobulin, a Low-Abundance Serum Protein, by Immunoaffinity Peptide Enrichment and Tandem Mass Spectrometry

(2008) A. N. Hoofnagle et al.   CLINICAL CHEMISTRY

Differential Membrane Proteomics Using18O-Labeling To Identify Biomarkers for Cholangiocarcinoma

(2008) Troels Zakarias Kristiansen et al.   JOURNAL OF PROTEOME RESEARCH

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Next-generation high-density self-assembling functional protein arrays

(2008) Niroshan Ramachandran et al.   NATURE METHODS

The interface between biomarker discovery and clinical validation: The tar pit of the protein biomarker pipeline

(2008) Amanda G. Paulovich et al.   Proteomics Clinical Applications

Strategic paths for biomarker qualification

(2008) Federico M. Goodsaid et al.   TOXICOLOGY