Top-down proteomics in health and disease: Challenges and opportunities
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Top-down proteomics in health and disease: Challenges and opportunities
Authors
Keywords
-
Journal
PROTEOMICS
Volume 14, Issue 10, Pages 1195-1210
Publisher
Wiley
Online
2014-04-11
DOI
10.1002/pmic.201300432
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- MASH Suite: A User-Friendly and Versatile Software Interface for High-Resolution Mass Spectrometry Data Interpretation and Visualization
- (2014) Huseyin Guner et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Top Down Proteomics of Human Membrane Proteins from Enriched Mitochondrial Fractions
- (2013) Adam D. Catherman et al. ANALYTICAL CHEMISTRY
- Post-Translational Modification by Cysteine Protects Cu/Zn-Superoxide Dismutase from Oxidative Damage
- (2013) Jared R. Auclair et al. BIOCHEMISTRY
- Complete Protein Characterization Using Top-Down Mass Spectrometry and Ultraviolet Photodissociation
- (2013) Jared B. Shaw et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Significant Modifications of the Salivary Proteome Potentially Associated with Complications of Down Syndrome Revealed by Top-down Proteomics
- (2013) Tiziana Cabras et al. MOLECULAR & CELLULAR PROTEOMICS
- Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ
- (2013) Nikolay Burnaevskiy et al. NATURE
- Proteoform: a single term describing protein complexity
- (2013) Lloyd M Smith et al. NATURE METHODS
- Mass spectrometry of intact membrane protein complexes
- (2013) Arthur Laganowsky et al. Nature Protocols
- Top-down proteomics reveals a unique protein S-thiolation switch in Salmonella Typhimurium in response to infection-like conditions
- (2013) C. Ansong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ultrahigh pressure fast size exclusion chromatography for top-down proteomics
- (2013) Xin Chen et al. PROTEOMICS
- The emergence of top-down proteomics in clinical research
- (2013) John P Savaryn et al. Genome Medicine
- Application of Metal-Coded Affinity Tags (MeCAT): Absolute Protein Quantification with Top-Down and Bottom-Up Workflows by Metal-Coded Tagging
- (2012) U. Bergmann et al. ANALYTICAL CHEMISTRY
- In-Spray Supercharging of Peptides and Proteins in Electrospray Ionization Mass Spectrometry
- (2012) Saša M. Miladinović et al. ANALYTICAL CHEMISTRY
- Top-down Targeted Proteomics for Deep Sequencing of Tropomyosin Isoforms
- (2012) Ying Peng et al. JOURNAL OF PROTEOME RESEARCH
- Top-Down Proteomics and Direct Surface Sampling of Neonatal Dried Blood Spots: Diagnosis of Unknown Hemoglobin Variants
- (2012) Rebecca L. Edwards et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Dynamically Harmonized FT-ICR Cell with Specially Shaped Electrodes for Compensation of Inhomogeneity of the Magnetic Field. Computer Simulations of the Electric Field and Ion Motion Dynamics
- (2012) Yury I. Kostyukevich et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Electron Transfer Dissociation Mass Spectrometry of Hemoglobin on Clinical Samples
- (2012) Didia Coelho Graça et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Next-generation proteomics: towards an integrative view of proteome dynamics
- (2012) A. F. Maarten Altelaar et al. NATURE REVIEWS GENETICS
- Cerebrospinal fluid top-down proteomics evidenced the potential biomarker role of LVV- and VV-hemorphin-7 in posterior cranial fossa pediatric brain tumors
- (2012) Claudia Desiderio et al. PROTEOMICS
- Enhanced top-down characterization of histone post-translational modifications
- (2012) Zhixin Tian et al. GENOME BIOLOGY
- Unit Mass Baseline Resolution for an Intact 148 kDa Therapeutic Monoclonal Antibody by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
- (2011) Santosh G. Valeja et al. ANALYTICAL CHEMISTRY
- On the Scalability and Requirements of Whole Protein Mass Spectrometry
- (2011) Philip D. Compton et al. ANALYTICAL CHEMISTRY
- Heart Disease and Stroke Statistics—2012 Update
- (2011) et al. CIRCULATION
- Comprehensive Analysis of Protein Modifications by Top-Down Mass Spectrometry
- (2011) Han Zhang et al. Circulation-Cardiovascular Genetics
- Building Multidimensional Biomarker Views of Type 2 Diabetes on the Basis of Protein Microheterogeneity
- (2011) C. R. Borges et al. CLINICAL CHEMISTRY
- Mass spectrometry-based proteomics for systems biology
- (2011) Eduard Sabidó et al. CURRENT OPINION IN BIOTECHNOLOGY
- Intact proteome fractionation strategies compatible with mass spectrometry
- (2011) Alan A Doucette et al. Expert Review of Proteomics
- Analysis of Intact Protein Isoforms by Mass Spectrometry
- (2011) Jeremiah D. Tipton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Augmented Phosphorylation of Cardiac Troponin I in Hypertensive Heart Failure
- (2011) Xintong Dong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Top-Down Quantitative Proteomics Identified Phosphorylation of Cardiac Troponin I as a Candidate Biomarker for Chronic Heart Failure
- (2011) Jiang Zhang et al. JOURNAL OF PROTEOME RESEARCH
- Protein signatures for survival and recurrence in metastatic melanoma
- (2011) William M. Hardesty et al. Journal of Proteomics
- Protein Identification Using Top-Down Spectra
- (2011) Xiaowen Liu et al. MOLECULAR & CELLULAR PROTEOMICS
- A Mechanical Nanomembrane Detector for Time-of-Flight Mass Spectrometry
- (2011) Jonghoo Park et al. NANO LETTERS
- Mapping intact protein isoforms in discovery mode using top-down proteomics
- (2011) John C. Tran et al. NATURE
- The worldwide epidemiology of type 2 diabetes mellitus—present and future perspectives
- (2011) Lei Chen et al. Nature Reviews Endocrinology
- Epidemiology of Alzheimer disease
- (2011) Christiane Reitz et al. Nature Reviews Neurology
- Posttranslational Modification of Pili upon Cell Contact Triggers N. meningitidis Dissemination
- (2011) J. Chamot-Rooke et al. SCIENCE
- New Reagents for Enhanced Liquid Chromatographic Separation and Charging of Intact Protein Ions for Electrospray Ionization Mass Spectrometry
- (2010) Santosh G. Valeja et al. ANALYTICAL CHEMISTRY
- Rosiglitazone Revisited
- (2010) Steven E. Nissen et al. ARCHIVES OF INTERNAL MEDICINE
- Top-down analysis of small plasma proteins using an LTQ-Orbitrap. Potential for mass spectrometry-based clinical assays for transthyretin and hemoglobin
- (2010) Roger Théberge et al. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
- Classification of HER2 Receptor Status in Breast Cancer Tissues by MALDI Imaging Mass Spectrometry
- (2010) Sandra Rauser et al. JOURNAL OF PROTEOME RESEARCH
- Quantitative top-down proteomics of SILAC labeled human embryonic stem cells
- (2010) Timothy S. Collier et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Deciphering modifications in swine cardiac troponin I by top-down high-resolution tandem mass spectrometry
- (2010) Jiang Zhang et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Deconvolution and Database Search of Complex Tandem Mass Spectra of Intact Proteins
- (2010) Xiaowen Liu et al. MOLECULAR & CELLULAR PROTEOMICS
- High Resolution Electron Transfer Dissociation Studies of Unfractionated Intact Histones from Murine Embryonic Stem Cells Using On-line Capillary LC Separation
- (2010) Shannon M. Eliuk et al. MOLECULAR & CELLULAR PROTEOMICS
- The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput
- (2010) John F. Kellie et al. Molecular BioSystems
- Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis
- (2010) J. R. Auclair et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Quantitative analysis of intact apolipoproteins in human HDL by top-down differential mass spectrometry
- (2010) Matthew T. Mazur et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Achievements and perspectives of top-down proteomics
- (2010) Andrea Armirotti et al. PROTEOMICS
- In VivoPhosphorylation Site Mapping in Mouse Cardiac Troponin I by High Resolution Top-Down Electron Capture Dissociation Mass Spectrometry: Ser22/23 Are the Only Sites Basally Phosphorylated
- (2009) Serife Ayaz-Guner et al. BIOCHEMISTRY
- Decon2LS: An open-source software package for automated processing and visualization of high resolution mass spectrometry data
- (2009) Navdeep Jaitly et al. BMC BIOINFORMATICS
- A Common Property of Amyotrophic Lateral Sclerosis-associated Variants
- (2009) Kathleen S. Molnar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Single amino acid sequence polymorphisms in rat cardiac troponin revealed by top–down tandem mass spectrometry
- (2009) Raquel Sancho Solis et al. JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY
- Precursor ion independent algorithm for top-down shotgun proteomics
- (2009) Yihsuan S. Tsai et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Analysis of Human C1q by Combined Bottom-up and Top-down Mass Spectrometry
- (2009) Delphine Pflieger et al. MOLECULAR & CELLULAR PROTEOMICS
- S100A7, a Novel Alzheimer's Disease Biomarker with Non-Amyloidogenic α-Secretase Activity Acts via Selective Promotion of ADAM-10
- (2009) Weiping Qin et al. PLoS One
- Top-down high-resolution mass spectrometry of cardiac myosin binding protein C revealed that truncation alters protein phosphorylation state
- (2009) Y. Ge et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Top-Down Identification and Quantification of Stable Isotope Labeled Proteins fromAspergillus flavusUsing Online Nano-Flow Reversed-Phase Liquid Chromatography Coupled to a LTQ-FTICR Mass Spectrometer
- (2008) Timothy S. Collier et al. ANALYTICAL CHEMISTRY
- The unique functions of cardiac troponin I in the control of cardiac muscle contraction and relaxation
- (2008) R. John Solaro et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Combinatorial Modification of Human Histone H4 Quantitated by Two-dimensional Liquid Chromatography Coupled with Top Down Mass Spectrometry
- (2008) James J. Pesavento et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Increasing charge while preserving noncovalent protein complexes for ESI-MS
- (2008) Shirley H. Lomeli et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Unraveling Molecular Complexity of Phosphorylated Human Cardiac Troponin I by Top Down Electron Capture Dissociation/Electron Transfer Dissociation Mass Spectrometry
- (2008) Vlad Zabrouskov et al. MOLECULAR & CELLULAR PROTEOMICS
- Stepwise evolution of protein native structure with electrospray into the gas phase, 10-12 to 102 s
- (2008) K. Breuker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection
- (2008) T. I. Pollin et al. SCIENCE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started