Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment

In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome

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Preclinical Rationale for PI3K/Akt/mTOR Pathway Inhibitors as Therapy for Epidermal Growth Factor Receptor Inhibitor-Resistant Non–Small-Cell Lung Cancer

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Genotyping and Genomic Profiling of Non–Small-Cell Lung Cancer: Implications for Current and Future Therapies

(2013) Tianhong Li et al.   JOURNAL OF CLINICAL ONCOLOGY

Discovery of the Novel mTOR Inhibitor and Its Antitumor Activities In Vitro and In Vivo

(2013) H. Xie et al.   MOLECULAR CANCER THERAPEUTICS

Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions

(2013) Jung Ok Park et al.   PROTEOMICS

Tumor-derived exosomes and microvesicles in head and neck cancer: Implications for tumor biology and biomarker discovery

(2013) Simona Principe et al.   PROTEOMICS

Proteomics, transcriptomics and lipidomics of exosomes and ectosomes

(2013) Dong-Sic Choi et al.   PROTEOMICS

RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls

(2012) Mikkel Noerholm et al.   BMC CANCER

Resistance to Irreversible EGF Receptor Tyrosine Kinase Inhibitors through a Multistep Mechanism Involving the IGF1R Pathway

(2012) A. B. Cortot et al.   CANCER RESEARCH

The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer

(2012) Jayoung Kim et al.   CELL CYCLE

Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers

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EGFRmutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples

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Prognostic and Predictive Role of the VeriStrat Plasma Test in Patients with Advanced Non–Small-Cell Lung Cancer Treated with Erlotinib or Placebo in the NCIC Clinical Trials Group BR.21 Trial

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EGFR–TKI resistant non-small cell lung cancer (NSCLC): New developments and implications for future treatment

(2012) Wolfram Brugger et al.   LUNG CANCER

Exosomes as Biomarker Enriched Microvesicles: Characterization of Exosomal Proteins Derived from a Panel of Prostate Cell Lines with Distinct AR Phenotypes

(2012) Elham Hosseini-Beheshti et al.   MOLECULAR & CELLULAR PROTEOMICS

Harnessing a Physiologic Mechanism for siRNA Delivery With Mimetic Lipoprotein Particles

(2012) Tomoko Nakayama et al.   MOLECULAR THERAPY

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Therapeutic Effects of Autologous Tumor-Derived Nanovesicles on Melanoma Growth and Metastasis

(2012) Eun-Young Lee et al.   PLoS One

An In Vivo C. elegans Model System for Screening EGFR-Inhibiting Anti-Cancer Drugs

(2012) Young-Ki Bae et al.   PLoS One

RAD001 Enhances the Potency of BEZ235 to Inhibit mTOR Signaling and Tumor Growth

(2012) Beat Nyfeler et al.   PLoS One

Circulating Endothelial Cells and Microparticles as Prognostic Markers in Advanced Non-Small Cell Lung Cancer

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Reactivation of ERK Signaling Causes Resistance to EGFR Kinase Inhibitors

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Microvesicles Released from Human Renal Cancer Stem Cells Stimulate Angiogenesis and Formation of Lung Premetastatic Niche

(2011) C. Grange et al.   CANCER RESEARCH

EGFR Protein Expression in Non-Small Cell Lung Cancer Predicts Response to an EGFR Tyrosine Kinase Inhibitor--A Novel Antibody for Immunohistochemistry or AQUA Technology

(2011) C. Mascaux et al.   CLINICAL CANCER RESEARCH

Comprehensive Proteome Analysis of Malignant Pleural Effusion for Lung Cancer Biomarker Discovery by Using Multidimensional Protein Identification Technology

(2011) Chia-Jung Yu et al.   JOURNAL OF PROTEOME RESEARCH

Epidermal Growth Factor Receptor Mutation Status in Circulating Free DNA in Serum: From IPASS, a Phase III Study of Gefitinib or Carboplatin/Paclitaxel in Non-small Cell Lung Cancer

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The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts

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(2010) Anita Mrvar-Brečko et al.   BLOOD CELLS MOLECULES AND DISEASES

Reciprocal and Complementary Role of MET Amplification and EGFR T790M Mutation in Acquired Resistance to Kinase Inhibitors in Lung Cancer

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Microvesicles: mediators of extracellular communication during cancer progression

(2010) V. Muralidharan-Chari et al.   JOURNAL OF CELL SCIENCE

EGFR T790M Mutation: A Double Role in Lung Cancer Cell Survival?

(2010) Kenichi Suda et al.   Journal of Thoracic Oncology

Hypoxic Tumor Cell Modulates Its Microenvironment to Enhance Angiogenic and Metastatic Potential by Secretion of Proteins and Exosomes

(2010) Jung Eun Park et al.   MOLECULAR & CELLULAR PROTEOMICS

Microvesicle-mediated RNA Molecule Delivery System Using Monocytes/Macrophages

(2010) Yukihiro Akao et al.   MOLECULAR THERAPY

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(2009) A. Lachmann et al.   BIOINFORMATICS

Effects of Src inhibitors on cell growth and epidermal growth factor receptor and MET signaling in gefitinib-resistant non-small cell lung cancer cells with acquired MET amplification

(2009) Takeshi Yoshida et al.   CANCER SCIENCE

ARF6-Regulated Shedding of Tumor Cell-Derived Plasma Membrane Microvesicles

(2009) Vandhana Muralidharan-Chari et al.   CURRENT BIOLOGY

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(2009) Ali I Musani   CURRENT OPINION IN PULMONARY MEDICINE

Discovery of Retinoblastoma-Associated Binding Protein 46 as a Novel Prognostic Marker for Distant Metastasis in Nonsmall Cell Lung Cancer by Combined Analysis of Cancer Cell Secretome and Pleural Effusion Proteome

(2009) Chih-Liang Wang et al.   JOURNAL OF PROTEOME RESEARCH

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(2009) Kenichiro Ito et al.   LUNG CANCER

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Cellular Microvesicle Pathways Can Be Targeted to Transfer Genetic Information between Non-Immune Cells

(2009) Amy M. Skinner et al.   PLoS One

The APEX Quantitative Proteomics Tool: Generating protein quantitation estimates from LC-MS/MS proteomics results

(2008) John C Braisted et al.   BMC BIOINFORMATICS

N-glycoprotein profiling of lung adenocarcinoma pleural effusions by shotgun proteomics

(2008) Alex Soltermann et al.   CANCER