The top-down, middle-down, and bottom-up mass spectrometry approaches for characterization of histone variants and their post-translational modifications

Data-Dependent Middle-Down Nano-Liquid Chromatography–Electron Capture Dissociation-Tandem Mass Spectrometry: An Application for the Analysis of Unfractionated Histones

(2013) Anastasia Kalli et al.   ANALYTICAL CHEMISTRY

Legionella pneumophila Effector RomA Uniquely Modifies Host Chromatin to Repress Gene Expression and Promote Intracellular Bacterial Replication

(2013) Monica Rolando et al.   Cell Host & Microbe

Proteoform: a single term describing protein complexity

(2013) Lloyd M Smith et al.   NATURE METHODS

Epigenetics and Cardiovascular Disease

(2012) Andrew L.H. Webster et al.   CANADIAN JOURNAL OF CARDIOLOGY

Proteomics in chromatin biology and epigenetics: Elucidation of post-translational modifications of histone proteins by mass spectrometry

(2012) Simone Sidoli et al.   Journal of Proteomics

Quantitative Assessment of Chromatin Immunoprecipitation Grade Antibodies Directed against Histone Modifications Reveals Patterns of Co-occurring Marks on Histone Protein Molecules

(2012) Sally E. Peach et al.   MOLECULAR & CELLULAR PROTEOMICS

Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent Acquisition: A New Concept for Consistent and Accurate Proteome Analysis

(2012) Ludovic C. Gillet et al.   MOLECULAR & CELLULAR PROTEOMICS

Epigenetic regulation of pancreas development and function

(2012) Dana Avrahami et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Enhanced top-down characterization of histone post-translational modifications

(2012) Zhixin Tian et al.   GENOME BIOLOGY

Advancements in Top-Down Proteomics

(2011) Hu Zhou et al.   ANALYTICAL CHEMISTRY

Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

(2011) Minjia Tan et al.   CELL

Revealing histone variant induced changes via quantitative proteomics

(2011) Anna M. Arnaudo et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

ADP-ribosylation of histones by ARTD1: An additional module of the histone code?

(2011) Michael O. Hottiger   FEBS LETTERS

Protein Identification Using Top-Down Spectra

(2011) Xiaowen Liu et al.   MOLECULAR & CELLULAR PROTEOMICS

Epigenetic treatment of neurological disease

(2011) Steven G Gray   Epigenomics

100% protein sequence coverage: a modern form of surrealism in proteomics

(2010) Bjoern Meyer et al.   AMINO ACIDS

Cancer Epigenetics

(2010) Rodolphe Taby et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The significance, development and progress of high-throughput combinatorial histone code analysis

(2010) Nicolas L. Young et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

High-Throughput Middle-Down Analysis Using an Orbitrap

(2010) Joe Cannon et al.   JOURNAL OF PROTEOME RESEARCH

Deconvolution and Database Search of Complex Tandem Mass Spectra of Intact Proteins

(2010) Xiaowen Liu et al.   MOLECULAR & CELLULAR PROTEOMICS

High Resolution Electron Transfer Dissociation Studies of Unfractionated Intact Histones from Murine Embryonic Stem Cells Using On-line Capillary LC Separation

(2010) Shannon M. Eliuk et al.   MOLECULAR & CELLULAR PROTEOMICS

Electron capture dissociation of highly charged proteolytic peptides from Lys N, Lys C and Glu C digestion

(2010) Anastasia Kalli et al.   Molecular BioSystems

An assessment of histone-modification antibody quality

(2010) Thea A Egelhofer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A combined top-down and bottom-up MS approach for the characterization of hemoglobin variants in Rhesus monkeys

(2010) Ruth Hüttenhain et al.   PROTEOMICS

Intact mass detection, interpretation, and visualization to automate Top-Down proteomics on a large scale

(2010) Kenneth R. Durbin et al.   PROTEOMICS

Two-dimensional liquid chromatography system for online top-down mass spectrometry

(2010) Zhixin Tian et al.   PROTEOMICS

YADA: a tool for taking the most out of high-resolution spectra

(2009) Paulo C. Carvalho et al.   BIOINFORMATICS

What does the future hold for top down mass spectrometry?

(2009) Benjamin A. Garcia   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

A Mixed Integer Linear Optimization Framework for the Identification and Quantification of Targeted Post-translational Modifications of Highly Modified Proteins Using Multiplexed Electron Transfer Dissociation Tandem Mass Spectrometry

(2009) Peter A. DiMaggio et al.   MOLECULAR & CELLULAR PROTEOMICS

Data Processing Algorithms for Analysis of High Resolution MSMS Spectra of Peptides with Complex Patterns of Posttranslational Modifications

(2009) Shenheng Guan et al.   MOLECULAR & CELLULAR PROTEOMICS

High Throughput Characterization of Combinatorial Histone Codes

(2009) Nicolas L. Young et al.   MOLECULAR & CELLULAR PROTEOMICS

Combinatorial Modification of Human Histone H4 Quantitated by Two-dimensional Liquid Chromatography Coupled with Top Down Mass Spectrometry

(2008) James J. Pesavento et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tissue-Specific Expression and Post-Translational Modification of Histone H3 Variants

(2008) Benjamin A. Garcia et al.   JOURNAL OF PROTEOME RESEARCH

Tandem Mass Spectrometry with Ultrahigh Mass Accuracy Clarifies Peptide Identification by Database Retrieval

(2008) Michael T. Boyne et al.   JOURNAL OF PROTEOME RESEARCH

Mass spectrometry identifies and quantifies 74 unique histone H4 isoforms in differentiating human embryonic stem cells

(2008) D. Phanstiel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA