Subtoxic and toxic concentrations of benzene and toluene induce Nrf2-mediated antioxidative stress response and affect the central carbon metabolism in lung epithelial cells A549

Benzo[a]pyrene affects Jurkat T cells in the activated state via the antioxidant response element dependent Nrf2 pathway leading to decreased IL-2 secretion and redirecting glutamine metabolism

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Alternatives to animal testing: current status and future perspectives

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Semi-targeted analysis of metabolites using capillary-flow ion chromatography coupled to high-resolution mass spectrometry

(2011) Karl Burgess et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

The aromatic volatile organic compounds toluene, benzene and styrene induce COX-2 and prostaglandins in human lung epithelial cells via oxidative stress and p38 MAPK activation

(2011) Iljana Mögel et al.   TOXICOLOGY

Optimization of parameters for coverage of low molecular weight proteins

(2010) Stephan A. Müller et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Chlorinated Benzenes Cause Concomitantly Oxidative Stress and Induction of Apoptotic Markers in Lung Epithelial Cells (A549) at Nonacute Toxic Concentrations

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Nrf2 plays an important role in coordinated regulation of Phase II drug metabolism enzymes and Phase III drug transporters

(2009) Guoxiang Shen et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

The aryl hydrocarbon receptor has an important role in the regulation of hematopoiesis: Implications for benzene-induced hematopoietic toxicity

(2009) Thomas A. Gasiewicz et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Proteome changes in human bronchoalveolar cells following styrene exposure indicate involvement of oxidative stress in the molecular-response mechanism

(2009) Nora Mörbt et al.   PROTEOMICS

Comparative Analysis of the Venom Proteomes ofVipera ammodytes ammodytesandVipera ammodytes meridionalis

(2008) Dessislava Georgieva et al.   JOURNAL OF PROTEOME RESEARCH

Déjà vu in proteomics. A hit parade of repeatedly identified differentially expressed proteins

(2008) Jiri Petrak et al.   PROTEOMICS

Incorporation of carbon and nitrogen atoms into proteins measured by protein-based stable isotope probing (Protein-SIP)

(2008) Nico Jehmlich et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Pathway analysis tools and toxicogenomics reference databases for risk assessment

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