The methylproteome and the intracellular methylation network

Expanding Cofactor Repertoire of Protein Lysine Methyltransferase for Substrate Labeling

(2011) Kabirul Islam et al.   ACS Chemical Biology

Structure and Mechanisms of Lysine Methylation Recognition by the Chromodomain in Gene Transcription

(2011) Kyoko L. Yap et al.   BIOCHEMISTRY

JAK2V617F-Mediated Phosphorylation of PRMT5 Downregulates Its Methyltransferase Activity and Promotes Myeloproliferation

(2011) Fan Liu et al.   CANCER CELL

Protein-arginine Methyltransferase 1 (PRMT1) Methylates Ash2L, a Shared Component of Mammalian Histone H3K4 Methyltransferase Complexes

(2011) Jill S. Butler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ribosomal L1 Protuberance in Yeast Is Methylated on a Lysine Residue Catalyzed by a Seven-β-strand Methyltransferase

(2011) Kristofor J. Webb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

More than 100,000 Detectable Peptide Species Elute in Single Shotgun Proteomics Runs but the Majority is Inaccessible to Data-Dependent LC−MS/MS

(2011) Annette Michalski et al.   JOURNAL OF PROTEOME RESEARCH

Labeling Substrates of Protein Arginine Methyltransferase with Engineered Enzymes and MatchedS-Adenosyl-l-methionine Analogues

(2011) Rui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

(2011) Craig J. Ceol et al.   NATURE

A differential proteome screening system for post-translational modification–dependent transcription factor interactions

(2011) Ole Pless et al.   Nature Protocols

Four-dimensional visualisation and analysis of protein-protein interaction networks

(2011) Apurv Goel et al.   PROTEOMICS

Proteome Half-Life Dynamics in Living Human Cells

(2011) E. Eden et al.   SCIENCE

The C-Terminal Domain of RNA Polymerase II Is Modified by Site-Specific Methylation

(2011) R. J. Sims et al.   SCIENCE

An enzyme-coupled ultrasensitive luminescence assay for protein methyltransferases

(2010) Glorymar Ibáñez et al.   ANALYTICAL BIOCHEMISTRY

Development of homogeneous luminescence assays for histone demethylase catalysis and binding

(2010) Akane Kawamura et al.   ANALYTICAL BIOCHEMISTRY

Regulation of post-translational protein arginine methylation during HeLa cell cycle

(2010) Chongtae Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Demethylation of RB Regulator MYPT1 by Histone Demethylase LSD1 Promotes Cell Cycle Progression in Cancer Cells

(2010) H.-S. Cho et al.   CANCER RESEARCH

Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein

(2010) Simon M Carr et al.   EMBO JOURNAL

srGAP2 Arginine Methylation Regulates Cell Migration and Cell Spreading through Promoting Dimerization

(2010) Shaoshi Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Methylation of Ribosomal Protein S10 by Protein-arginine Methyltransferase 5 Regulates Ribosome Biogenesis

(2010) Jinqi Ren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel 3-Methylhistidine Modification of Yeast Ribosomal Protein Rpl3 Is Dependent upon the YIL110W Methyltransferase

(2010) Kristofor J. Webb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Arginine Methylation Facilitates Cotranscriptional Recruitment of Pre-mRNA Splicing Factors

(2010) Y.-C. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

Lysine Methylation Regulates E2F1-Induced Cell Death

(2010) Haroula Kontaki et al.   MOLECULAR CELL

Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding

(2010) Zhigang Guo et al.   Nature Chemical Biology

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

(2010) Dan Levy et al.   NATURE IMMUNOLOGY

Yeast arginine methyltransferase Hmt1p regulates transcription elongation and termination by methylating Npl3p

(2010) Chi-Ming Wong et al.   NUCLEIC ACIDS RESEARCH

Analysis of Jmjd6 Cellular Localization and Testing for Its Involvement in Histone Demethylation

(2010) Phillip Hahn et al.   PLoS One

A Global Protein Kinase and Phosphatase Interaction Network in Yeast

(2010) A. Breitkreutz et al.   SCIENCE

A fast and efficient method for quantitative measurement of S-adenosyl-l-methionine-dependent methyltransferase activity with protein substrates

(2009) Brenda B. Suh-Lailam et al.   ANALYTICAL BIOCHEMISTRY

Arginine methylation of ribosomal protein S3 affects ribosome assembly

(2009) Hyun-Seock Shin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structure and function of histone methylation binding proteinsThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

(2009) Melanie A. Adams-Cioaba et al.   Biochemistry and Cell Biology

Analysis of arginine and lysine methylation utilizing peptide separations at neutral pH and electron transfer dissociation mass spectrometry

(2009) Ambrosius P. L. Snijders et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

High Throughput Characterization of Combinatorial Histone Codes

(2009) Nicolas L. Young et al.   MOLECULAR & CELLULAR PROTEOMICS

Protein Arginine Methylation in Mammals: Who, What, and Why

(2009) Mark T. Bedford et al.   MOLECULAR CELL

Minireview: Protein Arginine Methylation of Nonhistone Proteins in Transcriptional Regulation

(2009) Young-Ho Lee et al.   MOLECULAR ENDOCRINOLOGY

Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi

(2009) C. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing

(2009) Celia J. Webby et al.   SCIENCE

Protein arginine methylation in estrogen signaling and estrogen-related cancers

(2009) Catherine Teyssier et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Complications in the Assignment of 14 and 28 Da Mass Shift Detected by Mass Spectrometry as in Vivo Methylation from Endogenous Proteins

(2008) Sung Yun Jung et al.   ANALYTICAL CHEMISTRY

The emerging field of dynamic lysine methylation of non-histone proteins

(2008) Jing Huang et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

A Conserved SET Domain Methyltransferase, Set11, Modifies Ribosomal Protein Rpl12 in Fission Yeast

(2008) Mahito Sadaie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Two SET Domain Proteins Required for Methylation of Lysine Residues in Yeast Ribosomal Protein Rpl42ab

(2008) Kristofor J. Webb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global Analysis of Gel Mobility of Proteins and Its Use in Target Identification

(2008) Atsuko Shirai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Validation of Eukaryotic Aspartate and Glutamate Methylation in Proteins

(2008) Robert Sprung et al.   JOURNAL OF PROTEOME RESEARCH

Immonium Ion Scanning for the Discovery of Post-Translational Modifications and Its Application to Histones

(2008) Timothy A. Couttas et al.   JOURNAL OF PROTEOME RESEARCH

Turnover of the Human Proteome: Determination of Protein Intracellular Stability by Dynamic SILAC

(2008) Mary K. Doherty et al.   JOURNAL OF PROTEOME RESEARCH

Accurate localization and relative quantification of arginine methylation using nanoflow liquid chromatography coupled to electron transfer dissociation and drbitrap mass spectrometry

(2008) Hao Wang et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Specificity of protein lysine methyltransferases and methods for detection of lysine methylation of non-histone proteins

(2008) Philipp Rathert et al.   Molecular BioSystems

Methylation of p53 by Set7/9 Mediates p53 Acetylation and Activity In Vivo

(2008) Julia K. Kurash et al.   MOLECULAR CELL

Arginine Methylation of FOXO Transcription Factors Inhibits Their Phosphorylation by Akt

(2008) Kazuyuki Yamagata et al.   MOLECULAR CELL

Protein lysine methyltransferase G9a acts on non-histone targets

(2008) Philipp Rathert et al.   Nature Chemical Biology

The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules

(2008) Robert E Collins et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states

(2008) Floor Frederiks et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

High-Quality Binary Protein Interaction Map of the Yeast Interactome Network

(2008) H. Yu et al.   SCIENCE