Proteomic technologies for the identification of disease biomarkers in serum: Advances and challenges ahead

Investigation of the Ovarian and Prostate Cancer Peptidome for Candidate Early Detection Markers Using a Novel Nanoparticle Biomarker Capture Technology

(2010) Claudia Fredolini et al.   AAPS Journal

Label-Free Biomarker Sensing in Undiluted Serum with Suspended Microchannel Resonators

(2010) Marcio G. von Muhlen et al.   ANALYTICAL CHEMISTRY

Nanotechniques in proteomics: Current status, promises and challenges

(2010) Sandipan Ray et al.   BIOSENSORS & BIOELECTRONICS

p53 Autoantibodies as Potential Detection and Prognostic Biomarkers in Serous Ovarian Cancer

(2010) K. S. Anderson et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Mass Spectrometry-Based Protein Biomarker Discovery: Solving the Remaining Challenges to Reach the Promise of Clinical Benefit

(2010) L. A. Liotta et al.   CLINICAL CHEMISTRY

Applications of Current Proteomics Techniques in Modern Drug Design

(2010) Cheng-Cheng Zhang et al.   Current Computer-Aided Drug Design

Differential Proteomics Identification of HSP90 as Potential Serum Biomarker in Hepatocellular Carcinoma by Two-dimensional Electrophoresis and Mass Spectrometry

(2010) Yiyi Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Quantitative Proteomics Analysis of Maternal Plasma in Down Syndrome Pregnancies Using Isobaric Tagging Reagent (iTRAQ)

(2010) Varaprasad Kolla et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Combination of Improved18O Incorporation and Multiple Reaction Monitoring: A Universal Strategy for Absolute Quantitative Verification of Serum Candidate Biomarkers of Liver Cancer

(2010) Yan Zhao et al.   JOURNAL OF PROTEOME RESEARCH

Proteomics of Hepatocellular Carcinoma: Serum Vimentin As a Surrogate Marker for Small Tumors (≤2 cm)

(2010) Stella Sun et al.   JOURNAL OF PROTEOME RESEARCH

Use of a Single-Chain Antibody Library for Ovarian Cancer Biomarker Discovery

(2010) Arturo B. Ramirez et al.   MOLECULAR & CELLULAR PROTEOMICS

Detection of multiple autoantibodies in patients with ankylosing spondylitis using nucleic acid programmable protein arrays

(2010) C. Wright et al.   MOLECULAR & CELLULAR PROTEOMICS

Reverse phase protein microarrays advance to use in clinical trials

(2010) Claudius Mueller et al.   Molecular Oncology

Plasma proteome profiling reveals biomarker patterns associated with prognosis and therapy selection in glioblastoma multiforme patients

(2010) Anders Carlsson et al.   Proteomics Clinical Applications

Serum Vasopressin Concentrations During Orthotopic Liver Transplantation

(2010) M.T. Keegan et al.   TRANSPLANTATION PROCEEDINGS

Progressive degradation of serum samples limits proteomic biomarker discovery

(2009) Shadab Ahmad et al.   ANALYTICAL BIOCHEMISTRY

Single-Wall Carbon Nanotube Forest Arrays for Immunoelectrochemical Measurement of Four Protein Biomarkers for Prostate Cancer

(2009) Bhaskara V. Chikkaveeraiah et al.   ANALYTICAL CHEMISTRY

Label-Free Quantitation of a Cancer Biomarker in Complex Media Using Silicon Photonic Microring Resonators

(2009) Adam L. Washburn et al.   ANALYTICAL CHEMISTRY

Label-Free Electrical Detection of Cardiac Biomarker with Complementary Metal-Oxide Semiconductor-Compatible Silicon Nanowire Sensor Arrays

(2009) Jay Huiyi Chua et al.   ANALYTICAL CHEMISTRY

Rapid and Label-Free Detection of Breast Cancer Biomarker CA15-3 in Clinical Human Serum Samples with Optofluidic Ring Resonator Sensors

(2009) Hongying Zhu et al.   ANALYTICAL CHEMISTRY

Real-time label-free detection of complement activation products in human serum by white light reflectance spectroscopy

(2009) Panagiota S. Petrou et al.   BIOSENSORS & BIOELECTRONICS

Comparison of surface plasmon resonance and capacitive immunosensors for cancer antigen 125 detection in human serum samples

(2009) Siriwan Suwansa-ard et al.   BIOSENSORS & BIOELECTRONICS

The Bottleneck in the Cancer Biomarker Pipeline and Protein Quantification through Mass Spectrometry-Based Approaches: Current Strategies for Candidate Verification

(2009) S. Makawita et al.   CLINICAL CHEMISTRY

The Clinical Plasma Proteome: A Survey of Clinical Assays for Proteins in Plasma and Serum

(2009) N. L. Anderson   CLINICAL CHEMISTRY

The identification of phosphoglycerate kinase-1 and histone H4 autoantibodies in pancreatic cancer patient serum using a natural protein microarray

(2009) Tasneem H. Patwa et al.   ELECTROPHORESIS

Searching for serum tumor markers for colorectal cancer using a 2-D DIGE approach

(2009) Yanlei Ma et al.   ELECTROPHORESIS

Serum proteomics of glioma: methods and applications

(2009) Kumaravel Somasundaram et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Serum proteomics and biomarker discovery across the spectrum of nonalcoholic fatty liver disease

(2009) Lauren N. Bell et al.   HEPATOLOGY

Proteomic Analysis of Serum in Lung Cancer Induced by 3-Methylcholanthrene

(2009) Minhua Li et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

A label-free nano-liquid chromatography–mass spectrometry approach for quantitative serum peptidomics in Crohn's disease patients

(2009) Paolo Nanni et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Nanoparticle technology: Addressing the fundamental roadblocks to protein biomarker discovery

(2009) Alessandra Luchini et al.   JOURNAL OF MATERIALS CHEMISTRY

Serum levels of complement C4 fragments correlate with disease activity in multiple sclerosis: Proteomic analysis

(2009) Setsu Sawai et al.   JOURNAL OF NEUROIMMUNOLOGY

Differential Secreted Proteome Approach in Murine Model for Candidate Biomarker Discovery in Colon Cancer

(2009) Kannan Rangiah et al.   JOURNAL OF PROTEOME RESEARCH

Identification of S100A8 and S100A9 as Serological Markers for Colorectal Cancer

(2009) Hye-Jung Kim et al.   JOURNAL OF PROTEOME RESEARCH

A Comparison of Labeling and Label-Free Mass Spectrometry-Based Proteomics Approaches

(2009) Vibhuti J. Patel et al.   JOURNAL OF PROTEOME RESEARCH

Mass Spectrometry (LC-MS/MS) Site-Mapping of N-Glycosylated Membrane Proteins for Breast Cancer Biomarkers

(2009) Stephen A. Whelan et al.   JOURNAL OF PROTEOME RESEARCH

Identification of Serum Biomarkers for Colorectal Cancer Metastasis Using a Differential Secretome Approach

(2009) Hua Xue et al.   JOURNAL OF PROTEOME RESEARCH

Profiling Protein Markers Associated with Lymph Node Metastasis in Prostate Cancer by DIGE-based Proteomics Analysis

(2009) Jun Pang et al.   JOURNAL OF PROTEOME RESEARCH

Design of high-density antibody microarrays for disease proteomics: Key technological issues

(2009) Carl A.K. Borrebaeck et al.   Journal of Proteomics

Multidimensional protein fractionation of blood proteins coupled to data-independent nanoLC–MS/MS analysis

(2009) Yishai Levin et al.   Journal of Proteomics

The stability of the circulating human proteome to variations in sample collection and handling procedures measured with an aptamer-based proteomics array

(2009) Rachel Ostroff et al.   Journal of Proteomics

Mass spectrometry-based serum proteome pattern analysis in molecular diagnostics of early stage breast cancer

(2009) Monika Pietrowska et al.   Journal of Translational Medicine

Sensitivity enhancement of a dynamic mode microcantilever by stress inducer and mass inducer to detect PSA at low picogram levels

(2009) Sang-Myung Lee et al.   LAB ON A CHIP

Identification of Novel Serological Biomarkers for Inflammatory Bowel Disease Using Escherichia coli Proteome Chip

(2009) Chien-Sheng Chen et al.   MOLECULAR & CELLULAR PROTEOMICS

Protein expression profiles in pediatric multiple sclerosis: potential biomarkers

(2009) KN Rithidech et al.   Multiple Sclerosis Journal

Core-Shell Hydrogel Particles Harvest, Concentrate and Preserve Labile Low Abundance Biomarkers

(2009) Caterina Longo et al.   PLoS One

Serum S100A6 Concentration Predicts Peritoneal Tumor Burden in Mice with Epithelial Ovarian Cancer and Is Associated with Advanced Stage in Patients

(2009) Bih-Rong Wei et al.   PLoS One

Development of reverse phase protein microarrays for the validation of clusterin, a mid-abundant blood biomarker

(2009) Adriana Aguilar-Mahecha et al.   Proteome Science

Comparative protein profiling of serum and plasma using an antibody suspension bead array approach

(2009) Jochen M. Schwenk et al.   PROTEOMICS

Cell-free synthesis-based protein microarrays and their applications

(2009) Harini Chandra et al.   PROTEOMICS

Label-free detection techniques for protein microarrays: Prospects, merits and challenges

(2009) Sandipan Ray et al.   PROTEOMICS

High-throughput ultra-high-performance liquid chromatography/tandem mass spectrometry quantitation of insulin-like growth factor-I and leucine-rich α-2-glycoprotein in serum as biomarkers of recombinant human growth hormone administration

(2009) R. G. Kay et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

A reagentless amperometric immunosensor for α-1-fetoprotein based on gold nanowires and ZnO nanorods modified electrode

(2008) Xuxiao Lu et al.   ANALYTICA CHIMICA ACTA

Label-free detection of cancer biomarker candidates using surface plasmon resonance imaging

(2008) Jon Ladd et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

ssDNA Aptamer-Based Surface Plasmon Resonance Biosensor for the Detection of Retinol Binding Protein 4 for the Early Diagnosis of Type 2 Diabetes

(2008) Su Jin Lee et al.   ANALYTICAL CHEMISTRY

Detection of human proteins using arrayed imaging reflectometry

(2008) Charles R. Mace et al.   BIOSENSORS & BIOELECTRONICS

Peptide-coated nanotube-based biosensor for the detection of disease-specific autoantibodies in human serum

(2008) Katerina A. Drouvalakis et al.   BIOSENSORS & BIOELECTRONICS

Disposable electrochemical immunosensor for carcinoembryonic antigen using ferrocene liposomes and MWCNT screen-printed electrode

(2008) Subramanian Viswanathan et al.   BIOSENSORS & BIOELECTRONICS

Comparative study of SPR and ELISA methods based on analysis of CD166/ALCAM levels in cancer and control human sera

(2008) Hana Vaisocherová et al.   BIOSENSORS & BIOELECTRONICS

Electrical detection of VEGFs for cancer diagnoses using anti-vascular endotherial growth factor aptamer-modified Si nanowire FETs

(2008) Hyun-Seung Lee et al.   BIOSENSORS & BIOELECTRONICS

The temporal profile of the anti-PF4/heparin immune response

(2008) A. Greinacher et al.   BLOOD

Serum proteome analysis for profiling protein markers associated with carcinogenesis and lymph node metastasis in nasopharyngeal carcinoma

(2008) Qiulin Liao et al.   CLINICAL & EXPERIMENTAL METASTASIS

Serum  2-HS Glycoprotein Predicts Survival in Patients with Glioblastoma

(2008) V. Petrik et al.   CLINICAL CHEMISTRY

Direct detection of carcinoembryonic antigen autoantibodies in clinical human serum samples using a surface plasmon resonance sensor

(2008) Jon Ladd et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Antibody microarray analysis of directly labelled complex proteomes

(2008) Christer Wingren et al.   CURRENT OPINION IN BIOTECHNOLOGY

Serum proteome profiling of metastatic breast cancer using recombinant antibody microarrays

(2008) Anders Carlsson et al.   EUROPEAN JOURNAL OF CANCER

Quantitative mass spectrometry-based techniques for clinical use: Biomarker identification and quantification☆

(2008) Kathryn L. Simpson et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Multiple reaction monitoring for quantitative biomarker analysis in proteomics and metabolomics☆

(2008) Neil R. Kitteringham et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

IPO-38 Is Identified as a Novel Serum Biomarker of Gastric Cancer Based on Clinical Proteomics Technology

(2008) Yuan Hao et al.   JOURNAL OF PROTEOME RESEARCH

Antibody Suspension Bead Arrays within Serum Proteomics

(2008) Jochen M. Schwenk et al.   JOURNAL OF PROTEOME RESEARCH

Application of Protein Microarrays for Multiplexed Detection of Antibodies to Tumor Antigens in Breast Cancer

(2008) Karen S. Anderson et al.   JOURNAL OF PROTEOME RESEARCH

Glycoproteomics for Prostate Cancer Detection: Changes in Serum PSA Glycosylation Patterns

(2008) Danni L. Meany et al.   JOURNAL OF PROTEOME RESEARCH

Robust and Sensitive iTRAQ Quantification on an LTQ Orbitrap Mass Spectrometer

(2008) Marcus Bantscheff et al.   MOLECULAR & CELLULAR PROTEOMICS

Quantitative Serum Proteomics from Surface Plasmon Resonance Imaging

(2008) Christopher Lausted et al.   MOLECULAR & CELLULAR PROTEOMICS

Clinical Quantitation of Prostate-specific Antigen Biomarker in the Low Nanogram/Milliliter Range by Conventional Bore Liquid Chromatography-Tandem Mass Spectrometry (Multiple Reaction Monitoring) Coupling and Correlation with ELISA Tests

(2008) Tanguy Fortin et al.   MOLECULAR & CELLULAR PROTEOMICS

Concentration and preservation of very low abundance biomarkers in urine, such as human growth hormone (hGH), by Cibacron Blue F3G-A loaded hydrogel particles

(2008) Claudia Fredolini et al.   Nano Research

Nanotubes light up protein arrays

(2008) Sanjeeva Srivastava et al.   NATURE BIOTECHNOLOGY

Protein microarrays with carbon nanotubes as multicolor Raman labels

(2008) Zhuo Chen et al.   NATURE BIOTECHNOLOGY

Proteomics, nanotechnology and molecular diagnostics

(2008) Christopher J. Johnson et al.   PROTEOMICS

Profiling humoral immune responses to P. falciparum infection with protein microarrays

(2008) Denise L. Doolan et al.   PROTEOMICS

Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: Accurate detection of CA19-9 levels in pancreatic cancer

(2008) Tobias Grote et al.   PROTEOMICS

7thHUPO World Congress of Proteomics: Launching the Second Phase of the HUPO Plasma Proteome Project (PPP-2) 16-20 August 2008, Amsterdam, The Netherlands

(2008) Gilbert S. Omenn et al.   PROTEOMICS

Applications of protein microarrays for biomarker discovery

(2008) Niroshan Ramachandran et al.   Proteomics Clinical Applications

Label-free, all-electrical, in situ human epidermal growth receptor 2 detection

(2008) Joseph A. Capobianco et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

Combination of affinity depletion of abundant proteins and reversed-phase fractionation in proteomic analysis of human plasma/serum

(2007) Nina Zolotarjova et al.   JOURNAL OF CHROMATOGRAPHY A