Azacytidine induces necrosis of multiple myeloma cells through oxidative stress

The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways

(2012) Zhigao Wang et al.   CELL

The Odyssey of Hsp60 from Tumor Cells to Other Destinations Includes Plasma Membrane-Associated Stages and Golgi and Exosomal Protein-Trafficking Modalities

(2012) Claudia Campanella et al.   PLoS One

Programmed necrosis: backup to and competitor with apoptosis in the immune system

(2011) Jiahuai Han et al.   NATURE IMMUNOLOGY

Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma

(2010) B. A. Walker et al.   BLOOD

DNA Methylation Analysis Determines the High Frequency of Genic Hypomethylation and Low Frequency of Hypermethylation Events in Plasma Cell Tumors

(2010) B. Salhia et al.   CANCER RESEARCH

Calreticulin: non-endoplasmic reticulum functions in physiology and disease

(2009) Leslie I. Gold et al.   FASEB JOURNAL

Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

(2009) Pierre Fenaux et al.   LANCET ONCOLOGY

HYD1-induced increase in reactive oxygen species leads to autophagy and necrotic cell death in multiple myeloma cells

(2009) R. R. Nair et al.   MOLECULAR CANCER THERAPEUTICS

The Inflammatory Response to Cell Death

(2008) Kenneth L. Rock et al.   Annual Review of Pathology-Mechanisms of Disease

Oxidative Stress by Targeted Agents Promotes Cytotoxicity in Hematologic Malignancies

(2008) Joya Chandra   ANTIOXIDANTS & REDOX SIGNALING

Combination of DNA methylation inhibitor 5-azacytidine and arsenic trioxide has synergistic activity in myeloma

(2008) Guanghua Chen et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

The effect of azacitidine on interleukin-6 signaling and nuclear factor- B activation and its in vitro and in vivo activity against multiple myeloma

(2008) T. Khong et al.   HAEMATOLOGICA

Semenogelin I expression in myeloma cells can be upregulated pharmacologically

(2008) Yana Zhang et al.   LEUKEMIA RESEARCH

Potentiation of reactive oxygen species is a marker for synergistic cytotoxicity of MS-275 and 5-azacytidine in leukemic cells

(2007) Shan Gao et al.   LEUKEMIA RESEARCH