Protein misfolding in the late-onset neurodegenerative diseases: Common themes and the unique case of amyotrophic lateral sclerosis

Emotional Dysfunction in Parkinson’s Disease

(2014) Lee X. Blonder et al.   BEHAVIOURAL NEUROLOGY

TDP-43 skeins show properties of amyloid in a subset of ALS cases

(2012) John L. Robinson et al.   ACTA NEUROPATHOLOGICA

Amyotrophic lateral sclerosis and frontotemporal dementia: A behavioural and cognitive continuum

(2012) Patricia Lillo et al.   Amyotrophic Lateral Sclerosis

Propagation of the Prion Phenomenon: Beyond the Seeding Principle

(2012) Christian Münch et al.   JOURNAL OF MOLECULAR BIOLOGY

Early Steps in Oxidation-Induced SOD1 Misfolding: Implications for Non-Amyloid Protein Aggregation in Familial ALS

(2012) Vikram Khipple Mulligan et al.   JOURNAL OF MOLECULAR BIOLOGY

Direct three-dimensional visualization of membrane disruption by amyloid fibrils

(2012) L. Milanesi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Unifying Role for Prions in Neurodegenerative Diseases

(2012) S. B. Prusiner   SCIENCE

Optineurin is co-localized with FUS in basophilic inclusions of ALS with FUS mutation and in basophilic inclusion body disease

(2011) Hidefumi Ito et al.   ACTA NEUROPATHOLOGICA

Optineurin inclusions occur in a minority of TDP-43 positive ALS and FTLD-TDP cases and are rarely observed in other neurodegenerative disorders

(2011) Tibor Hortobágyi et al.   ACTA NEUROPATHOLOGICA

A novel SOD1 mutation in amyotrophic lateral sclerosis with a distinct clinical phenotype

(2011) Jun Hu et al.   Amyotrophic Lateral Sclerosis

Analyzing complicated protein folding kinetics rapidly by analytical Laplace inversion using a Tikhonov regularization variant

(2011) Vikram Khipple Mulligan et al.   ANALYTICAL BIOCHEMISTRY

Solid-State NMR Studies of Amyloid Fibril Structure

(2011) Robert Tycko   Annual Review of Physical Chemistry

Lack of Evidence for the Efficacy of Memantine in Mild Alzheimer Disease

(2011) Lon S. Schneider   ARCHIVES OF NEUROLOGY

A partially folded structure of amyloid-beta(1–40) in an aqueous environment

(2011) Subramanian Vivekanandan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Aβ42 oligomers, but not fibrils, simultaneously bind to and cause damage to ganglioside-containing lipid membranes

(2011) Thomas L. Williams et al.   BIOCHEMICAL JOURNAL

Glutathionylation at Cys-111 Induces Dissociation of Wild Type and FALS Mutant SOD1 Dimers

(2011) Rachel L. Redler et al.   BIOCHEMISTRY

Defective Protein Folding and Aggregation as the Basis of Neurodegenerative Diseases: The Darker Aspect of Proteins

(2011) Aabgeena Naeem et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Cholera in the 21st century

(2011) Richelle C. Charles et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Current and Emerging Drug Treatment Options for Alzheimerʼs Disease

(2011) Nathan Herrmann et al.   DRUGS

Mitochondrial dysfunction in familial amyotrophic lateral sclerosis

(2011) Liesbeth Faes et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Cutting Off Functional Loops from Homodimeric Enzyme Superoxide Dismutase 1 (SOD1) Leaves Monomeric β-Barrels

(2011) Jens Danielsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ALS-Causing SOD1 Mutations Promote Production of Copper-Deficient Misfolded Species

(2011) Philbert Ip et al.   JOURNAL OF MOLECULAR BIOLOGY

Local Unfolding of Cu, Zn Superoxide Dismutase Monomer Determines the Morphology of Fibrillar Aggregates

(2011) Feng Ding et al.   JOURNAL OF MOLECULAR BIOLOGY

Propagation: Prion-like mechanisms can explain spreading of motor neuronal death in amyotrophic lateral sclerosis?

(2011) S. Kuwabara et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Generalization of the Prion Hypothesis to Other Neurodegenerative Diseases: An Imperfect Fit

(2011) Will C. Guest et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Measles

(2011) William J Moss et al.   LANCET

Leprosy now: epidemiology, progress, challenges, and research gaps

(2011) Laura C Rodrigues et al.   LANCET INFECTIOUS DISEASES

Clinical genetics of amyotrophic lateral sclerosis: what do we really know?

(2011) Peter M. Andersen et al.   Nature Reviews Neurology

Clinical diagnosis and management of amyotrophic lateral sclerosis

(2011) Orla Hardiman et al.   Nature Reviews Neurology

Novel optineurin mutations in sporadic amyotrophic lateral sclerosis patients

(2011) Marka van Blitterswijk et al.   NEUROBIOLOGY OF AGING

Selective Neuronal Vulnerability in Neurodegenerative Diseases: from Stressor Thresholds to Degeneration

(2011) Smita Saxena et al.   NEURON

Near Elimination of Varicella Deaths in the US After Implementation of the Vaccination Program

(2011) M. Marin et al.   PEDIATRICS

Implications of the prion-related Q/N domains in TDP-43 and FUS

(2011) Maria Udan et al.   Prion

Vaccines in the time of cholera

(2011) J. D. Clemens   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS

(2011) K. A. Vassall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysfunction of constitutive and inducible ubiquitin-proteasome system in amyotrophic lateral sclerosis: Implication for protein aggregation and immune response

(2011) Caterina Bendotti et al.   PROGRESS IN NEUROBIOLOGY

Influenza: Epidemiology, Clinical Features, Therapy, and Prevention

(2011) Nina Clark et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

WHO initiative to increase global and equitable access to influenza vaccine in the event of a pandemic: Supporting developing country production capacity through technology transfer

(2011) Martin Friede et al.   VACCINE

Proteostasis and Movement Disorders: Parkinson's Disease and Amyotrophic Lateral Sclerosis

(2011) D. A. Bosco et al.   Cold Spring Harbor Perspectives in Biology

Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form

(2010) Aaron Kerman et al.   ACTA NEUROPATHOLOGICA

From Emergence to Eradication: The Epidemiology of Poliomyelitis Deconstructed

(2010) N. Nathanson et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Characterization of a Covalent Polysulfane Bridge in Copper−Zinc Superoxide Dismutase,

(2010) Zheng You et al.   BIOCHEMISTRY

A Review of the Neural Mechanisms of Action and Clinical Efficiency of Riluzole in Treating Amyotrophic Lateral Sclerosis: What have we Learned in the Last Decade?

(2010) Mark C. Bellingham   CNS Neuroscience & Therapeutics

Riluzole, Neuroprotection and Amyotrophic Lateral Sclerosis

(2010) B.C. Cheah et al.   CURRENT MEDICINAL CHEMISTRY

BCG vaccination and leprosy protection: review of current evidence and status of BCG in leprosy control

(2010) Corinne SC Merle et al.   Expert Review of Vaccines

Nonamyloid Aggregates Arising from Mature Copper/Zinc Superoxide Dismutases Resemble Those Observed in Amyotrophic Lateral Sclerosis

(2010) Young-Mi Hwang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Prion Diseases

(2010) Khalilah Brown et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Disulfide-Reduced ALS Variants of Cu, Zn Superoxide Dismutase Exhibit Increased Populations of Unfolded Species

(2010) Can Kayatekin et al.   JOURNAL OF MOLECULAR BIOLOGY

Mutations of optineurin in amyotrophic lateral sclerosis

(2010) Hirofumi Maruyama et al.   NATURE

Metal-Free ALS Variants of Dimeric Human Cu,Zn-Superoxide Dismutase Have Enhanced Populations of Monomeric Species

(2010) Anna-Karin E. Svensson et al.   PLoS One

Thioflavine T interaction with synthetic Alzheimer's disease β-amyloid peptides: Detection of amyloid aggregation in solution

(2010) Harry Levine   PROTEIN SCIENCE

Aggregation of Copper–Zinc Superoxide Dismutase in Familial and Sporadic ALS

(2009) Madhuri Chattopadhyay et al.   ANTIOXIDANTS & REDOX SIGNALING

Incidence and lifetime risk of motor neuron disease in the United Kingdom: a population-based study

(2009) A. Alonso et al.   EUROPEAN JOURNAL OF NEUROLOGY

Oxidative stress in ALS: Key role in motor neuron injury and therapeutic target

(2009) Siân C. Barber et al.   FREE RADICAL BIOLOGY AND MEDICINE

Parkinson's disease: from monogenic forms to genetic susceptibility factors

(2009) S. Lesage et al.   HUMAN MOLECULAR GENETICS

Modifications of Superoxide Dismutase (SOD1) in Human Erythrocytes

(2009) Kyle C. Wilcox et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficacy and safety of a modified killed-whole-cell oral cholera vaccine in India: an interim analysis of a cluster-randomised, double-blind, placebo-controlled trial

(2009) Dipika Sur et al.   LANCET

Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria

(2009) Dennis W Dickson et al.   LANCET NEUROLOGY

ALS motor phenotype heterogeneity, focality, and spread: Deconstructing motor neuron degeneration

(2009) J. M. Ravits et al.   NEUROLOGY

Functional features cause misfolding of the ALS-provoking enzyme SOD1

(2009) A. Nordlund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and dynamic aspects related to oligomerization of apo SOD1 and its mutants

(2009) L. Banci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stopping tuberculosis in the 21st century: Goals and strategies

(2009) Ikushi ONOZAKI et al.   RESPIROLOGY

Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

(2009) C. Vance et al.   SCIENCE

Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis

(2009) T. J. Kwiatkowski et al.   SCIENCE

Non-HIV Viral Infections of the Salivary Glands

(2009) Andrea Schreiber et al.   Oral and Maxillofacial Surgery Clinics of North America

Zinc Binding Modulates the Entire Folding Free Energy Surface of Human Cu,Zn Superoxide Dismutase

(2008) Can Kayatekin et al.   JOURNAL OF MOLECULAR BIOLOGY

Denaturational Stress Induces Formation of Zinc-Deficient Monomers of Cu,Zn Superoxide Dismutase: Implications for Pathogenesis in Amyotrophic Lateral Sclerosis

(2008) Vikram Khipple Mulligan et al.   JOURNAL OF MOLECULAR BIOLOGY

Unfolding and Folding Kinetics of Amyotrophic Lateral Sclerosis-Associated Mutant Cu,Zn Superoxide Dismutases

(2008) Jessica A.O. Rumfeldt et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure and Dynamics of the Aβ21–30Peptide from the Interplay of NMR Experiments and Molecular Simulations

(2008) Nicolas L. Fawzi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mumps

(2008) Anders Hviid et al.   LANCET

ALS precursor finally shaken into fibrils

(2008) F. Rousseau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Initiation and elongation in fibrillation of ALS-linked superoxide dismutase

(2008) M. Chattopadhyay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Homology versus analogy: possible evolutionary relationship of immunoglobulins, cupredoxins, and Cu,Zn-superoxide dismutase

(2007) Fred J. Stevens   JOURNAL OF MOLECULAR RECOGNITION

Sonication of proteins causes formation of aggregates that resemble amyloid

(2004) Peter B. Stathopulos et al.   PROTEIN SCIENCE