Signatures of the ATP-binding pocket as a basis for structural classification of the serine/threonine protein kinases of gram-positive bacteria

Bacterial Eukaryotic Type Serine-Threonine Protein Kinases: From Structural Biology to Targeted Anti-Infective Drug Design

(2011) Valery N. Danilenko et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Fighting Tumor Cell Survival: Advances in the Design and Evaluation of Pim Inhibitors

(2010) F. Anizon et al.   CURRENT MEDICINAL CHEMISTRY

Archaeal Eukaryote-Like Serine/Threonine Protein Kinase Interacts with and Phosphorylates a Forkhead-Associated-Domain-Containing Protein

(2010) B. Wang et al.   JOURNAL OF BACTERIOLOGY

Analyzing the Topology of Active Sites: On the Prediction of Pockets and Subpockets

(2010) Andrea Volkamer et al.   Journal of Chemical Information and Modeling

Pocket Similarity: Are α Carbons Enough?

(2010) Howard J Feldman et al.   Journal of Chemical Information and Modeling

Protein Pockets: Inventory, Shape, and Comparison

(2010) Ryan G. Coleman et al.   Journal of Chemical Information and Modeling

A computational workflow for the design of irreversible inhibitors of protein kinases

(2010) Alberto Del Rio et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

GenBank

(2010) D. A. Benson et al.   NUCLEIC ACIDS RESEARCH

ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

(2010) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

A Framework for Classification of Prokaryotic Protein Kinases

(2010) Nidhi Tyagi et al.   PLoS One

Combining Structure and Sequence Information Allows Automated Prediction of Substrate Specificities within Enzyme Families

(2010) Marc Röttig et al.   PLoS Computational Biology

Protein Kinase G Is Required for Intrinsic Antibiotic Resistance in Mycobacteria

(2009) K. A. Wolff et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The highly conserved serine threonine kinase StkP of Streptococcus pneumoniae contributes to penicillin susceptibility independently from genes encoding penicillin-binding proteins

(2009) Ricardo Dias et al.   BMC MICROBIOLOGY

Signaling mechanisms of the Mycobacterium tuberculosis receptor Ser/Thr protein kinases

(2009) Tom Alber   CURRENT OPINION IN STRUCTURAL BIOLOGY

Binding Site Similarity Analysis for the Functional Classification of the Protein Kinase Family

(2009) Sarah L. Kinnings et al.   Journal of Chemical Information and Modeling

Sequence-Derived Three-Dimensional Pharmacophore Models for G-Protein-Coupled Receptors and Their Application in Virtual Screening

(2009) Thomas Klabunde et al.   JOURNAL OF MEDICINAL CHEMISTRY

Human gut microbiota and bifidobacteria: from composition to functionality

(2008) Francesca Turroni et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Effect of mutation K85R on GSK-3β: Molecular dynamics simulation

(2008) Hao Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Auto-activation mechanism of the Mycobacterium tuberculosis PknB receptor Ser/Thr kinase

(2008) Carl Mieczkowski et al.   EMBO JOURNAL

Assessment of Chemical Coverage of Kinome Space and Its Implications for Kinase Drug Discovery

(2008) Paul Bamborough et al.   JOURNAL OF MEDICINAL CHEMISTRY

A quantitative analysis of kinase inhibitor selectivity

(2008) Mazen W Karaman et al.   NATURE BIOTECHNOLOGY

Mycobacterial Ser/Thr protein kinases and phosphatases: Physiological roles and therapeutic potential

(2007) Annemarie Wehenkel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Theoretical Modeling of PrkCc, Serine–Threonine Protein Kinase Intracellular Domain, Complexed with ATP Derivatives

(2007) Paweł Gruszczyński et al.   Quantitative structure-activity relationships & combinatorial science