Leukocyte integrin αLβ2 transmembrane association dynamics revealed by coarse-grained molecular dynamics simulations

Shedding of Large Functionally Active CD11/CD18 Integrin Complexes from Leukocyte Membranes during Synovial Inflammation Distinguishes Three Types of Arthritis through Differential Epitope Exposure

(2010) L. C. Gjelstrup et al.   JOURNAL OF IMMUNOLOGY

A Transmembrane Polar Interaction Is Involved in the Functional Regulation of Integrin αLβ2

(2010) Ardcharaporn Vararattanavech et al.   JOURNAL OF MOLECULAR BIOLOGY

Integrins as therapeutic targets: lessons and opportunities

(2010) Dermot Cox et al.   NATURE REVIEWS DRUG DISCOVERY

Lipid-mediated interactions tune the association of glycophorin A helix and its disruptive mutants in membranes

(2010) Durba Sengupta et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Comment on “On using a too large integration time step in molecular dynamics simulations of coarse-grained molecular models” by M. Winger, D. Trzesniak, R. Baron and W. F. van Gunsteren, Phys. Chem. Chem. Phys., 2009, 11, 1934

(2010) Siewert J. Marrink et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Molecular Dynamics Simulations of the Dimerization of Transmembrane α-Helices

(2009) Emi Psachoulia et al.   ACCOUNTS OF CHEMICAL RESEARCH

The structure of the integrin αIIbβ3 transmembrane complex explains integrin transmembrane signalling

(2009) Tong-Lay Lau et al.   EMBO JOURNAL

Intermonomer Hydrogen Bonds Enhance GxxxG-Driven Dimerization of the BNIP3 Transmembrane Domain: Roles for Sequence Context in Helix–Helix Association in Membranes

(2009) Charles M. Lawrie et al.   JOURNAL OF MOLECULAR BIOLOGY

The Structure of a Receptor with Two Associating Transmembrane Domains on the Cell Surface: Integrin αIIbβ3

(2009) Jieqing Zhu et al.   MOLECULAR CELL

Consensus motif for integrin transmembrane helix association

(2009) B. W. Berger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Permissive transmembrane helix heterodimerization is required for the expression of a functional integrin

(2008) Ardcharaporn Vararattanavech et al.   BIOCHEMICAL JOURNAL

Helix−Helix Interactions in Membrane Proteins: Coarse-Grained Simulations of Glycophorin A Helix Dimerization†

(2008) Emi Psachoulia et al.   BIOCHEMISTRY

Disruption of the Integrin αLβ2 Transmembrane Domain Interface by β2 Thr-686 Mutation Activates αLβ2 and Promotes Micro-clustering of the αL Subunits

(2008) Ardcharaporn Vararattanavech et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The MARTINI Coarse-Grained Force Field: Extension to Proteins

(2008) Luca Monticelli et al.   Journal of Chemical Theory and Computation

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Role of Hydrogen Bonding and Helix−Lipid Interactions in Transmembrane Helix Association

(2008) Jinhyuk Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY