The active-inactive transition of human thymidylate synthase: Targeted molecular dynamics simulations

Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability,

(2010) Xiao Huang et al.   BIOCHEMISTRY

T-Analyst: a program for efficient analysis of protein conformational changes by torsion angles

(2010) Rizi Ai et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Novel Approaches for Targeting Thymidylate Synthase To Overcome the Resistance and Toxicity of Anticancer Drugs

(2010) Divita Garg et al.   JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric Acetylation of the Cyclooxygenase-2 Homodimer by Aspirin and Its Effects on the Oxygenation of Arachidonic, Eicosapentaenoic, and Docosahexaenoic Acids

(2010) N. P. Sharma et al.   MOLECULAR PHARMACOLOGY

Comparison of Three Perturbation Molecular Dynamics Methods for Modeling Conformational Transitions

(2009) He Huang et al.   Journal of Chemical Theory and Computation

Segmented Transition Pathway of the Signaling Protein Nitrogen Regulatory Protein C

(2009) Ming Lei et al.   JOURNAL OF MOLECULAR BIOLOGY

Design and characterization of a mutation outside the active site of human thymidylate synthase that affects ligand binding

(2009) D. Cardinale et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Catalytically Requisite Conformational Dynamics in the mRNA-Capping Enzyme Probed by Targeted Molecular Dynamics†

(2008) Robert V. Swift et al.   BIOCHEMISTRY

The R163K Mutant of Human Thymidylate Synthase Is Stabilized in an Active Conformation: Structural Asymmetry and Reactivity of Cysteine 195†‡

(2008) Lydia M. Gibson et al.   BIOCHEMISTRY

Conformational transition pathway in the allosteric process of calcium-induced recoverin: Molecular dynamics simulations

(2008) Ji-Lai Li et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

The ConSurf-DB: pre-calculated evolutionary conservation profiles of protein structures

(2008) Ofir Goldenberg et al.   NUCLEIC ACIDS RESEARCH