Selective CGRP and adrenomedullin peptide binding by tethered RAMP-calcitonin receptor-like receptor extracellular domain fusion proteins

Identification of key residues involved in adrenomedullin binding to the AM1receptor

(2013) HA Watkins et al.   BRITISH JOURNAL OF PHARMACOLOGY

The structure of secretin family GPCR peptide ligands: implications for receptor pharmacology and drug development

(2012) Harriet A. Watkins et al.   DRUG DISCOVERY TODAY

Bacterial expression and purification of a heterodimeric adrenomedullin receptor extracellular domain complex using DsbC-assisted disulfide shuffling

(2012) Heather E. Hill et al.   PROTEIN EXPRESSION AND PURIFICATION

Calcitonin and calcitonin receptor-like receptors: common themes with family B GPCRs?

(2011) James Barwell et al.   BRITISH JOURNAL OF PHARMACOLOGY

Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors

(2011) Shiva Kumar et al.   PLoS One

Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding

(2011) Seisuke Kusano et al.   PROTEIN SCIENCE

Refolding and Characterization of a Soluble Ectodomain Complex of the Calcitonin Gene-Related Peptide Receptor

(2010) Christopher M. Koth et al.   BIOCHEMISTRY

Dimeric Arrangement of the Parathyroid Hormone Receptor and a Structural Mechanism for Ligand-induced Dissociation

(2010) Augen A. Pioszak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for Hormone Recognition by the Human CRFR2α G Protein-coupled Receptor

(2010) Kuntal Pal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism

(2010) Ernst ter Haar et al.   STRUCTURE

Structure-function relationships of the N-terminus of receptor activity-modifying proteins

(2009) Tao Qi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Calcitonin gene-related peptide: an update on the biology

(2009) Ana Recober et al.   CURRENT OPINION IN NEUROLOGY

Structural Basis for Parathyroid Hormone-related Protein Binding to the Parathyroid Hormone Receptor and Design of Conformation-selective Peptides

(2009) Augen A. Pioszak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1

(2008) Augen A. Pioszak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of N-Terminal Receptor Activity-Modifying Protein Residues Important for Calcitonin Gene-Related Peptide, Adrenomedullin, and Amylin Receptor Function

(2008) T. Qi et al.   MOLECULAR PHARMACOLOGY

Neuronal system-dependent facilitation of tumor angiogenesis and tumor growth by calcitonin gene-related peptide

(2008) M. Toda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular recognition of parathyroid hormone by its G protein-coupled receptor

(2008) Augen A. Pioszak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of the human receptor activity-modifying protein 1 extracellular domain

(2008) Seisuke Kusano et al.   PROTEIN SCIENCE