Exploring sequence requirements for C3/C4carboxylate recognition in thePseudomonas aeruginosacephalosporinase: Insights into plasticity of the AmpC β-lactamase

Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective

(2010) Olga Khersonsky and Dan S. Tawfik   Annual Review of Biochemistry

Prevalence, Resistance Mechanisms, and Susceptibility of Multidrug-Resistant Bloodstream Isolates of Pseudomonas aeruginosa

(2010) V. H. Tam et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Three Decades of  -Lactamase Inhibitors

(2010) S. M. Drawz et al.   CLINICAL MICROBIOLOGY REVIEWS

Emerging carbapenemases: a global perspective

(2010) Timothy R. Walsh   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Multiple Global Suppressors of Protein Stability Defects Facilitate the Evolution of Extended-Spectrum TEM β-Lactamases

(2010) Nicholas G. Brown et al.   JOURNAL OF MOLECULAR BIOLOGY

Extended-Spectrum Cephalosporinases in Pseudomonas aeruginosa

(2009) J.-M. Rodriguez-Martinez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Inhibition of the Class C β-Lactamase fromAcinetobacterspp.: Insights into Effective Inhibitor Design

(2009) Sarah M. Drawz et al.   BIOCHEMISTRY

Enhancing Resistance to Cephalosporins in Class C β-Lactamases: Impact of Gly214Glu in CMY-2

(2009) Andrea Endimiani et al.   BIOCHEMISTRY

Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 1. Discovery of a class C BLI for combination with imipinem

(2009) Timothy A. Blizzard et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The clinical consequences of antimicrobial resistance

(2009) Louis B Rice   CURRENT OPINION IN MICROBIOLOGY

Prospects for the next anti-Pseudomonas drug

(2009) Malcolm GP Page et al.   CURRENT OPINION IN PHARMACOLOGY

Protein structure prediction and model quality assessment

(2009) Andriy Kryshtafovych et al.   DRUG DISCOVERY TODAY

Analysis of the plasticity of location of the Arg244 positive charge within the active site of the TEM-1 β-lactamase

(2009) David C. Marciano et al.   PROTEIN SCIENCE

Crystal structure of a cold-adapted class C β-lactamase

(2008) Catherine Michaux et al.   FEBS Journal

Antimicrobial-Resistant Pathogens Associated With Healthcare-Associated Infections: Annual Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006–2007

(2008) Alicia I. Hidron et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Structure-function studies of arginine at position 276 in CTX-M  -lactamases

(2008) F. J. Perez-Llarena et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Strategic Design of an Effective β-Lactamase Inhibitor

(2008) Priyaranjan Pattanaik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adaptive protein evolution grants organismal fitness by improving catalysis and flexibility

(2008) P. E. Tomatis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-based optimization of cephalothin-analogue boronic acids as β-lactamase inhibitors

(2007) Stefania Morandi et al.   BIOORGANIC & MEDICINAL CHEMISTRY