Molecular Modeling Comparison of the Performance of NS5b Polymerase Inhibitor (PSI-7977) on Prevalent HCV Genotypes

Hepatitis C RNA-dependent RNA polymerase inhibitors: A review of structure–activity and resistance relationships; different scaffolds and mutations

(2012) Abdelrahman S. Mayhoub   BIOORGANIC & MEDICINAL CHEMISTRY

Antiviral strategies in hepatitis C virus infection

(2012) Christoph Sarrazin et al.   JOURNAL OF HEPATOLOGY

Hexapeptide Functionality of Cellulose as NS3 Protease Inhibitors

(2012) Medhat Ibrahim et al.   Medicinal Chemistry

Recent advances in drug discovery of benzothiadiazine and related analogs as HCV NS5B polymerase inhibitors

(2011) Debasis Das et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus

(2011) Yue-Lei Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY

From benzimidazole to indole-5-carboxamide Thumb Pocket I inhibitors of HCV NS5B polymerase. Part 1: Indole C-2 SAR and discovery of diamide derivatives with nanomolar potency in cell-based subgenomic replicons

(2011) Pierre L. Beaulieu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

In vitro selection and characterization of HCV replicons resistant to multiple non-nucleoside polymerase inhibitors

(2011) Leen Delang et al.   JOURNAL OF HEPATOLOGY

Mechanisms of non-response to antiviral treatment in chronic hepatitis C

(2011) Stephane Chevaliez et al.   Clinics and Research in Hepatology and Gastroenterology

Anti-HCV drugs in the pipeline

(2011) Priscilla L Yang et al.   Current Opinion in Virology

Resistance to anti-HCV protease inhibitors

(2011) Alexander J Thompson et al.   Current Opinion in Virology

Development of novel therapies for hepatitis C

(2010) Stanley M. Lemon et al.   ANTIVIRAL RESEARCH

Structure-based virtual screening, synthesis and SAR of novel inhibitors of hepatitis C virus NS5B polymerase

(2010) Tanaji T. Talele et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Mechanism of Activation of PSI-7851 and Its Diastereoisomer PSI-7977

(2010) Eisuke Murakami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Correlation to Protein Conformation of Wide-Angle X-ray Scatter Parameters

(2010) Wael M. Elshemey et al.   PROTEIN JOURNAL

Mixing the right hepatitis C inhibitor cocktail

(2010) Michael A. Gelman et al.   TRENDS IN MOLECULAR MEDICINE

Characterization of NS3 protease from an Egyptian HCV genotype 4a isolate

(2009) Mahmoud Mohamed Bahgat et al.   ARCHIVES OF VIROLOGY

Protease and helicase activities of hepatitis C virus genotype 4, 5, and 6 NS3–NS4A proteins

(2009) Marie-Josée Massariol et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

Structural and electronic properties of new fullerene derivatives and their possible application as HIV-1 protease inhibitors

(2009) Medhat Ibrahim et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY