SpeedyGenes: an improved gene synthesis method for the efficient production of error-corrected, synthetic protein libraries for directed evolution

GeneGenie: optimized oligomer design for directed evolution

(2014) Neil Swainston et al.   NUCLEIC ACIDS RESEARCH

Engineering an Enantioselective Amine Oxidase for the Synthesis of Pharmaceutical Building Blocks and Alkaloid Natural Products

(2013) Diego Ghislieri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Towards practical, high-capacity, low-maintenance information storage in synthesized DNA

(2013) Nick Goldman et al.   NATURE

Navigating the protein fitness landscape with Gaussian processes

(2013) P. A. Romero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Scientific discovery as a combinatorial optimisation problem: How best to navigate the landscape of possible experiments?

(2012) Douglas B. Kell   BIOESSAYS

Directed Evolution of the Enzyme Monoamine Oxidase (MAO-N): Highly Efficient Chemo-enzymatic Deracemisation of the Alkaloid (±)-Crispine A

(2012) Ian Rowles et al.   ChemCatChem

DNA synthesis, assembly and applications in synthetic biology

(2012) Siying Ma et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

RECENT ADVANCES IN RATIONAL APPROACHES FOR ENZYME ENGINEERING

(2012) Kerstin Steiner et al.   Computational and Structural Biotechnology Journal

The imminent role of protein engineering in synthetic biology

(2011) Jee Loon Foo et al.   BIOTECHNOLOGY ADVANCES

Patch oligodeoxynucleotide synthesis (POS): a novel method for synthesis of long DNA sequences and full-length genes

(2011) Guanghua Yang et al.   BIOTECHNOLOGY LETTERS

SeSaM-Tv-II Generates a Protein Sequence Space that is Unobtainable by epPCR

(2011) Hemanshu Mundhada et al.   CHEMBIOCHEM

DNA assembly for synthetic biology: from parts to pathways and beyond

(2011) Tom Ellis et al.   Integrative Biology

Error correction of microchip synthesized genes using Surveyor nuclease

(2011) Ishtiaq Saaem et al.   NUCLEIC ACIDS RESEARCH

Error correction in gene synthesis technology

(2011) Siying Ma et al.   TRENDS IN BIOTECHNOLOGY

Laboratory Evolution of Stereoselective Enzymes: A Prolific Source of Catalysts for Asymmetric Reactions

(2010) Manfred T. Reetz   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Classifying DNA assembly protocols for devising cellular architectures

(2010) Xi Wang et al.   BIOTECHNOLOGY ADVANCES

High-fidelity gene synthesis by retrieval of sequence-verified DNA identified using high-throughput pyrosequencing

(2010) Mark Matzas et al.   NATURE BIOTECHNOLOGY

Strategies for protein synthetic biology

(2010) Raik Grünberg et al.   NUCLEIC ACIDS RESEARCH

Synthesis of high-quality libraries of long (150mer) oligonucleotides by a novel depurination controlled process

(2010) Emily M. LeProust et al.   NUCLEIC ACIDS RESEARCH

Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome

(2010) D. G. Gibson et al.   SCIENCE

Advancing high-throughput gene synthesis technology

(2009) Jingdong Tian et al.   Molecular BioSystems

Genome engineering

(2009) Peter A Carr et al.   NATURE BIOTECHNOLOGY

Directed evolution drives the next generation of biocatalysts

(2009) Nicholas J Turner   Nature Chemical Biology

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

A modified method for PCR-directed gene synthesis from large number of overlapping oligodeoxyribonucleotides

(2008) Jessica Cherry et al.  

The Structure of Monoamine Oxidase from Aspergillus niger Provides a Molecular Context for Improvements in Activity Obtained by Directed Evolution

(2008) Kate E. Atkin et al.   JOURNAL OF MOLECULAR BIOLOGY

In silico modelling of directed evolution: Implications for experimental design and stepwise evolution

(2008) David C. Wedge et al.   JOURNAL OF THEORETICAL BIOLOGY

Complete Chemical Synthesis, Assembly, and Cloning of a Mycoplasma genitalium Genome

(2008) D. G. Gibson et al.   SCIENCE

Enzyme optimization: moving from blind evolution to statistical exploration of sequence–function space

(2008) Richard J. Fox et al.   TRENDS IN BIOTECHNOLOGY