The effects of affinity and valency of an albumin-binding domain (ABD) on the half-life of a single-chain diabody-ABD fusion protein

Bispecific Antibodies for Cancer Immunotherapy

(2010) Dafne Müller et al.   BIODRUGS

Epitope distance to the target cell membrane and antigen size determine the potency of T cell-mediated lysis by BiTE antibodies specific for a large melanoma surface antigen

(2010) Claudia Bluemel et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Importance of Neonatal FcR in Regulating the Serum Half-Life of Therapeutic Proteins Containing the Fc Domain of Human IgG1: A Comparative Study of the Affinity of Monoclonal Antibodies and Fc-Fusion Proteins to Human Neonatal FcR

(2010) Takuo Suzuki et al.   JOURNAL OF IMMUNOLOGY

Enhanced antibody half-life improves in vivo activity

(2010) Jonathan Zalevsky et al.   NATURE BIOTECHNOLOGY

Anti-serum albumin domain antibodies in the development of highly potent, efficacious and long-acting interferon

(2010) A. Walker et al.   PROTEIN ENGINEERING DESIGN & SELECTION

New Strategy for the Extension of the Serum Half-Life of Antibody Fragments

(2009) Sabrina Trüssel et al.   BIOCONJUGATE CHEMISTRY

Strategies to Extend Plasma Half-Lives of Recombinant Antibodies

(2009) Roland E. Kontermann   BIODRUGS

Next generation immunotherapeutics—honing the magic bullet

(2009) Carrie Enever et al.   CURRENT OPINION IN BIOTECHNOLOGY

The Versatile MHC Class I-related FcRn Protects IgG and Albumin from Degradation: Implications for Development of New Diagnostics and Therapeutics

(2009) Jan Terje Andersen et al.   Drug Metabolism and Pharmacokinetics

Cross-species Binding Analyses of Mouse and Human Neonatal Fc Receptor Show Dramatic Differences in Immunoglobulin G and Albumin Binding

(2009) Jan Terje Andersen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biodistribution of a Bispecific Single-chain Diabody and Its Half-life Extended Derivatives

(2009) Roland Stork et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-Glycosylation as Novel Strategy to Improve Pharmacokinetic Properties of Bispecific Single-chain Diabodies

(2008) Roland Stork et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Murine endoglin-specific single-chain Fv fragments for the analysis of vascular targeting strategies in mice

(2008) Dafne Müller et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Engineering of a femtomolar affinity binding protein to human serum albumin

(2008) A. Jonsson et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Mutational analysis of the interaction between albumin-binding domain from streptococcal protein G and human serum albumin

(2002) Martin Linhult et al.   PROTEIN SCIENCE