Creating novel proteins by combining design and selection

Crystal structure of a designed tetratricopeptide repeat module in complex with its peptide ligand

(2010) Aitziber L. Cortajarena et al.   FEBS Journal

Computational design of affinity and specificity at protein–protein interfaces

(2009) John Karanicolas et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Electrostatic Interactions of Hsp-organizing Protein Tetratricopeptide Domains with Hsp70 and Hsp90

(2009) Tommi Kajander et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploitation of binding energy for catalysis and design

(2009) Summer B. Thyme et al.   NATURE

Computer-aided design of functional protein interactions

(2009) Daniel J Mandell et al.   Nature Chemical Biology

Designed TPR Modules as Novel Anticancer Agents

(2008) Aitziber L. Cortajarena et al.   ACS Chemical Biology

Macromolecular Modeling with Rosetta

(2008) Rhiju Das et al.   Annual Review of Biochemistry

Ligand binding by repeat proteins: natural and designed

(2008) T GROVE et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Alternative binding proteins: Anticalins - harnessing the structural plasticity of the lipocalin ligand pocket to engineer novel binding activities

(2008) Arne Skerra   FEBS Journal

Kemp elimination catalysts by computational enzyme design

(2008) Daniela Röthlisberger et al.   NATURE

De Novo Computational Design of Retro-Aldol Enzymes

(2008) L. Jiang et al.   SCIENCE