MicroRNAs in prostate cancer: from biomarkers to molecularly-based therapeutics

Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer

(2011) S Kojima et al.   BRITISH JOURNAL OF CANCER

Control of cell proliferation pathways by microRNAs

(2011) María José Bueno et al.   CELL CYCLE

MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines

(2011) Giuditta Viticchiè et al.   CELL CYCLE

miR-183-96-182 Cluster Is Overexpressed in Prostate Tissue and Regulates Zinc Homeostasis in Prostate Cells

(2011) Brittany L. Mihelich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-143 decreases prostate cancer cells proliferation and migration and enhances their sensitivity to docetaxel through suppression of KRAS

(2011) Bin Xu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

(2011) Can Liu et al.   NATURE MEDICINE

MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4

(2011) K Schramedei et al.   ONCOGENE

Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancer

(2011) M Musumeci et al.   ONCOGENE

Identification of miRs-143 and -145 that Is Associated with Bone Metastasis of Prostate Cancer and Involved in the Regulation of EMT

(2011) Xinsheng Peng et al.   PLoS One

MicroRNAs Associated with Metastatic Prostate Cancer

(2011) Akira Watahiki et al.   PLoS One

MicroRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer

(2010) Shahana Majid et al.   CANCER

The Promise of MicroRNA Replacement Therapy

(2010) A. G. Bader et al.   CANCER RESEARCH

Development of a Lung Cancer Therapeutic Based on the Tumor Suppressor MicroRNA-34

(2010) J. F. Wiggins et al.   CANCER RESEARCH

Transcriptional Control of Gene Expression by MicroRNAs

(2010) Basel Khraiwesh et al.   CELL

Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs

(2010) Susana Gonzalez et al.   CELL CYCLE

Regulatory Role of mir-203 in Prostate Cancer Progression and Metastasis

(2010) Sharanjot Saini et al.   CLINICAL CANCER RESEARCH

The road toward microRNA therapeutics

(2010) Anita G. Seto   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Promise and Challenge of RNA Interference–Based Therapy for Cancer

(2010) Fabio Petrocca et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeting microRNAs in cancer: rationale, strategies and challenges

(2010) Ramiro Garzon et al.   NATURE REVIEWS DRUG DISCOVERY

miRBase: integrating microRNA annotation and deep-sequencing data

(2010) A. Kozomara et al.   NUCLEIC ACIDS RESEARCH

A study of miRNAs targets prediction and experimental validation

(2010) Yong Huang et al.   Protein & Cell

Metastamir: The Field of Metastasis-Regulatory microRNA Is Spreading

(2009) D. R. Hurst et al.   CANCER RESEARCH

miR-205 Exerts Tumor-Suppressive Functions in Human Prostate through Down-regulation of Protein Kinase C 

(2009) P. Gandellini et al.   CANCER RESEARCH

MicroRNA-17-3p is a prostate tumor suppressor in vitro and in vivo, and is decreased in high grade prostate tumors analyzed by laser capture microdissection

(2009) Xueping Zhang et al.   CLINICAL & EXPERIMENTAL METASTASIS

miR-331-3p Regulates ERBB-2 Expression and Androgen Receptor Signaling in Prostate Cancer

(2009) Michael R. Epis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes

(2009) Fumitaka Takeshita et al.   MOLECULAR THERAPY

MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation

(2009) K-H Lee et al.   ONCOGENE

miR-449a targets HDAC-1 and induces growth arrest in prostate cancer

(2009) E J Noonan et al.   ONCOGENE

miR-200 Regulates PDGF-D-Mediated Epithelial-Mesenchymal Transition, Adhesion, and Invasion of Prostate Cancer Cells

(2009) Dejuan Kong et al.   STEM CELLS

Change in expression of miR-let7c, miR-100, and miR-218 from high grade localized prostate cancer to metastasis

(2009) Katia R.M. Leite et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells

(2008) Yasunori Fujita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genomic Profiling of MicroRNA and Messenger RNA Reveals Deregulated MicroRNA Expression in Prostate Cancer

(2008) S. Ambs et al.   CANCER RESEARCH

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Ectopic expression of miR-126*, an intronic product of the vascular endothelial EGF-like 7 gene, regulates prostein translation and invasiveness of prostate cancer LNCaP cells

(2008) Alla Musiyenko et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation

(2008) Ulf Andersson Ørom et al.   MOLECULAR CELL

The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

(2008) Qihong Huang et al.   NATURE CELL BIOLOGY

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

(2008) Désirée Bonci et al.   NATURE MEDICINE

The Inhibition of the Highly Expressed Mir-221 and Mir-222 Impairs the Growth of Prostate Carcinoma Xenografts in Mice

(2008) Neri Mercatelli et al.   PLoS One

MicroRNA-directed transcriptional gene silencing in mammalian cells

(2008) D. H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-148 targets human DNMT3b protein coding region

(2008) A. M. Duursma et al.   RNA

Loss of mir-146a function in hormone-refractory prostate cancer

(2008) S.-L. Lin et al.   RNA

Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

(2008) S. Varambally et al.   SCIENCE