Exogenous SPARC Suppresses Proliferation and Migration of Prostate Cancer by Interacting With Integrin β1

Augmented Osteolysis in SPARC-Deficient Mice with Bone-Residing Prostate Cancer

(2015) N. Patrick McCabe et al.   NEOPLASIA

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Targeting Constitutively Activated β 1 Integrins Inhibits Prostate Cancer Metastasis

(2013) Yu-Chen Lee et al.   MOLECULAR CANCER RESEARCH

Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion

(2012) C. Tripodo et al.   BLOOD

Resistance to the mTOR-inhibitor RAD001 elevates integrin α2- and β1-triggered motility, migration and invasion of prostate cancer cells

(2012) I Tsaur et al.   BRITISH JOURNAL OF CANCER

Bone matrix osteonectin limits prostate cancer cell growth and survival

(2012) Kristina Kapinas et al.   MATRIX BIOLOGY

SPARC Overexpression Inhibits Cell Proliferation in Neuroblastoma and Is Partly Mediated by Tumor Suppressor Protein PTEN and AKT

(2012) Praveen Bhoopathi et al.   PLoS One

β1 integrin deletion enhances progression of prostate cancer in the TRAMP mouse model

(2012) Kim Moran-Jones et al.   Scientific Reports

SPARC Promotes Cathepsin B-Mediated Melanoma Invasiveness through a Collagen I/α2β1 Integrin Axis

(2011) María R. Girotti et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Astrocytes Control Glutamate Receptor Levels at Developing Synapses through SPARC- -Integrin Interactions

(2011) E. V. Jones et al.   JOURNAL OF NEUROSCIENCE

The role of the microenvironment in tumor growth and invasion

(2011) Yangjin Kim et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Targeting the PI3K/AKT Pathway for the Treatment of Prostate Cancer

(2009) D. Sarker et al.   CLINICAL CANCER RESEARCH

Role of the Akt Pathway in Prostate Cancer

(2009) Paul de Souza et al.   CURRENT CANCER DRUG TARGETS

Lymphadenectomy in minimally invasive urologic oncology

(2009) Alex J Vanni et al.   CURRENT OPINION IN UROLOGY

Prostate cancer stromal cells and LNCaP cells coordinately activate the androgen receptor through synthesis of testosterone and dihydrotestosterone from dehydroepiandrosterone

(2009) Atsushi Mizokami et al.   ENDOCRINE-RELATED CANCER

The role of SPARC in the TRAMP model of prostate carcinogenesis and progression

(2009) N Said et al.   ONCOGENE

Tranilast inhibits hormone refractory prostate cancer cell proliferation and suppresses transforming growth factor β1-associated osteoblastic changes

(2009) Kouji Izumi et al.   PROSTATE

The Tail of Integrins, Talin, and Kindlins

(2009) M. Moser et al.   SCIENCE

SPARC: a matricellular regulator of tumorigenesis

(2009) Shanna A. Arnold et al.   Journal of Cell Communication and Signaling

The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host

(2008) Osvaldo L. Podhajcer et al.   CANCER AND METASTASIS REVIEWS

SPARC in cancer biology: Its role in cancer progression and potential for therapy

(2008) Isabella T. Tai et al.   DRUG RESISTANCE UPDATES

Integrins in prostate cancer progression

(2008) H. L. Goel et al.   ENDOCRINE-RELATED CANCER

The Copper Binding Domain of SPARC Mediates Cell Survivalin Vitrovia Interaction with Integrin β1 and Activation of Integrin-linked Kinase

(2008) Matt S. Weaver et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A prototypic matricellular protein in the tumor microenvironment—Where there's SPARC, there's fire

(2008) Clancy J. Clark et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Can cancer be reversed by engineering the tumor microenvironment?

(2008) Donald E. Ingber   SEMINARS IN CANCER BIOLOGY