Crystalline silica-induced leukotriene B4-dependent inflammation promotes lung tumour growth

A novel immunocompetent murine model for replicating oncolytic adenoviral therapy

(2014) L Zhang et al.   CANCER GENE THERAPY

Suppressive oligodeoxynucleotides reduce lung cancer susceptibility in mice with silicosis

(2014) Christian Bode et al.   CARCINOGENESIS

Climbing RAS, the Everest of Oncogenes

(2014) M. Russo et al.   Cancer Discovery

Exposure-Response Analysis and Risk Assessment for Lung Cancer in Relationship to Silica Exposure: A 44-Year Cohort Study of 34,018 Workers

(2013) Y. Liu et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Neutralization of interleukin-1 beta attenuates silica-induced lung inflammation and fibrosis in C57BL/6 mice

(2013) Jiali Guo et al.   ARCHIVES OF TOXICOLOGY

Occupational exposure to crystalline silica and the risk of lung cancer in Canadian men

(2013) Linda Kachuri et al.   INTERNATIONAL JOURNAL OF CANCER

Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase

(2013) Lei Gong et al.   Molecular Cancer

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo

(2013) Tim Lämmermann et al.   NATURE

Neutralization of interleukin-17A delays progression of silica-induced lung inflammation and fibrosis in C57BL/6 mice

(2013) Ying Chen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Tumor-associated neutrophils: friend or foe?

(2012) Z. G. Fridlender et al.   CARCINOGENESIS

Leukotriene B4-Driven Neutrophil Recruitment to the Skin Is Essential for Allergic Skin Inflammation

(2012) Michiko K. Oyoshi et al.   IMMUNITY

Silicosis

(2012) Chi Chiu Leung et al.   LANCET

Crucial Involvement of Tumor-Associated Neutrophils in the Regulation of Chronic Colitis-Associated Carcinogenesis in Mice

(2012) Kun Shang et al.   PLoS One

Leukotriene B4 Receptor-1 Mediates Intermittent Hypoxia-induced Atherogenesis

(2011) Richard C. Li et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Neutrophilic airways inflammation in lung cancer: the role of exhaled LTB-4 and IL-8

(2011) Giovanna E Carpagnano et al.   BMC CANCER

Predictive clinical outcome of the intratumoral CD66b-positive neutrophil-to-CD8-positive T-cell ratio in patients with resectable nonsmall cell lung cancer

(2011) Marius Ilie et al.   CANCER

Tumor-Associated Neutrophils: New Targets for Cancer Therapy

(2011) A. D. Gregory et al.   CANCER RESEARCH

Inhibition of neutrophil infiltration into A549 lung tumors in vitro and in vivo using a CXCR2-specific antagonist is associated with reduced tumor growth

(2011) Simon Tazzyman et al.   INTERNATIONAL JOURNAL OF CANCER

Deficiency of the Leukotriene B4 Receptor, BLT-1, Protects against Systemic Insulin Resistance in Diet-Induced Obesity

(2011) M. Spite et al.   JOURNAL OF IMMUNOLOGY

An Exposure-Response Threshold for Lung Diseases and Lung Cancer Caused by Crystalline Silica

(2011) Louis Anthony Tony Cox Jr.   RISK ANALYSIS

Tobacco Smoke Promotes Lung Tumorigenesis by Triggering IKKβ- and JNK1-Dependent Inflammation

(2010) Hiroyuki Takahashi et al.   CANCER CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

The specific chymase inhibitor TY-51469 suppresses the accumulation of neutrophils in the lung and reduces silica-induced pulmonary fibrosis in mice

(2010) Hazuki Takato et al.   EXPERIMENTAL LUNG RESEARCH

Lipid-Cytokine-Chemokine Cascade Drives Neutrophil Recruitment in a Murine Model of Inflammatory Arthritis

(2010) Richard C. Chou et al.   IMMUNITY

Nonredundant Roles for Leukotriene B4 Receptors BLT1 and BLT2 in Inflammatory Arthritis

(2010) S. P. Mathis et al.   JOURNAL OF IMMUNOLOGY

Innate immune processes are sufficient for driving silicosis in mice

(2010) Celine A. Beamer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neutrophil elastase–mediated degradation of IRS-1 accelerates lung tumor growth

(2010) A McGarry Houghton et al.   NATURE MEDICINE

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

(2009) F. Colotta et al.   CARCINOGENESIS

Silica exposure, smoking, silicosis and lung cancer--complex interactions

(2009) T. Brown   OCCUPATIONAL MEDICINE-OXFORD

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE

Silica binding and toxicity in alveolar macrophages

(2007) Raymond F. Hamilton et al.   FREE RADICAL BIOLOGY AND MEDICINE