Carbon–carbon bond activation of cyclobutenones enabled by the addition of chiral organocatalyst to ketone

N-Heterocyclic Carbene Catalyzed Activation of Esters: A New Option for Asymmetric Domino Reactions

(2014) Pankaj Chauhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Rhodium(I)-Catalyzed Activation of Enantiotopic Cyclobutanone CC Bonds

(2014) Laetitia Souillart et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

DFT study on the reaction mechanisms and stereoselectivities of NHC-catalyzed [2 + 2] cycloaddition between arylalkylketenes and electron-deficient benzaldehydes

(2014) Mengmeng Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric Synthesis of Tri- and Tetrasubstituted Trifluoromethyl Dihydropyranones from α-Aroyloxyaldehydes via NHC Redox Catalysis

(2014) Alyn T. Davies et al.   ACS Catalysis

Highly Enantioselective γ-Amination by N-Heterocyclic Carbene Catalyzed [4+2] Annulation of Oxidized Enals and Azodicarboxylates

(2013) Xiang-Yu Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functionalization of Benzylic C(sp3)H Bonds of Heteroaryl Aldehydes through N-Heterocyclic Carbene Organocatalysis

(2013) Xingkuan Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acyl anion free N-heterocyclic carbene organocatalysis

(2013) Sarah J. Ryan et al.   CHEMICAL SOCIETY REVIEWS

Catalysis with N-Heterocyclic Carbenes under Oxidative Conditions

(2013) Suman De Sarkar et al.   CHEMISTRY-A EUROPEAN JOURNAL

NHC-Promoted Asymmetric β-Lactone Formation from Arylalkylketenes and Electron-Deficient Benzaldehydes or Pyridinecarboxaldehydes

(2013) James Douglas et al.   JOURNAL OF ORGANIC CHEMISTRY

Rhodium-Catalyzed Regioselective Carboacylation of Olefins: A CC Bond Activation Approach for Accessing Fused-Ring Systems

(2012) Tao Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Continuum of Progress: Applications of N-Hetereocyclic Carbene Catalysis in Total Synthesis

(2012) Javier Izquierdo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Rh-Catalyzed Carboacylation of Olefins: Efficient Syntheses of Chiral Poly-Fused Rings

(2012) Tao Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxidative γ-Addition of Enals to Trifluoromethyl Ketones: Enantioselectivity Control via Lewis Acid/N-Heterocyclic Carbene Cooperative Catalysis

(2012) Junming Mo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Extending NHC-Catalysis: Coupling Aldehydes with Unconventional Reaction Partners

(2011) Akkattu T. Biju et al.   ACCOUNTS OF CHEMICAL RESEARCH

N-Heterocyclic Carbene Catalyzed Domino Reactions

(2011) André Grossmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cyclobutanes in Catalysis

(2011) Tobias Seiser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Semipinacol Rearrangement in Natural Product Synthesis

(2011) Zhen-Lei Song et al.   CHEMICAL REVIEWS

Catalytic Kinetic Resolution of Cyclic Secondary Amines

(2011) Michael Binanzer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantum Mechanical Investigation of the Effect of Catalyst Fluorination in the Intermolecular Asymmetric Stetter Reaction

(2011) Joann M. Um et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective γ-Amination of α,β-Unsaturated Acyl Chlorides with Azodicarboxylates: Efficient Synthesis of Chiral γ-Amino Acid Derivatives

(2011) Li-Tao Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

On the Role of CO2in NHC-Catalyzed Oxidation of Aldehydes

(2011) Pei-Chen Chiang et al.   ORGANIC LETTERS

Formal Diels–Alder Reactions of Chalcones and Formylcyclopropanes Catalyzed by Chiral N-Heterocyclic Carbenes

(2011) Hui Lv et al.   ORGANIC LETTERS

Cooperative Lewis acid/N-heterocyclic carbene catalysis

(2011) Daniel T. Cohen et al.   Chemical Science

Enantioselective [4+2] cycloaddition of ketenes and 1-azadienes catalyzed by N-heterocyclic carbenes

(2010) Teng-Yue Jian et al.   CHEMICAL COMMUNICATIONS

NHC Catalyzed Oxidations of Aldehydes to Esters: Chemoselective Acylation of Alcohols in Presence of Amines

(2010) Suman De Sarkar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The spiropiperidine-3,3′-oxindole scaffold: a type II β-turn peptide isostere

(2010) Giordano Lesma et al.   TETRAHEDRON

Rhodium(I)-Catalyzed Enantioselective CC Bond Activation

(2009) Christian Winter et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Intramolecular Carbocyanation of Alkenes by CC Bond Activation

(2009) Carmen Nájera et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene-Catalyzed Domino Ring-Opening/Redox Amidation/Cyclization Reactions of Formylcyclopropane 1,1-Diesters: Direct Construction of a 6−5−6 Tricyclic Hydropyrido[1,2-a]indole Skeleton

(2009) Ding Du et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Asymmetric Vinylogous α-Ketol Rearrangement: Enantioselective Construction of Chiral All-Carbon Quaternary Stereocenters in Spirocyclic Diketones via Semipinacol-Type 1,2-Carbon Migration

(2009) En Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

α′-Hydroxyenones as Mechanistic Probes and Scope-Expanding Surrogates for α,β-Unsaturated Aldehydes in N-Heterocyclic Carbene-Catalyzed Reactions

(2009) Pei-Chen Chiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective metal-catalyzed activation of strained rings

(2009) Tobias Seiser et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective CC Bond Activation of Allenyl Cyclobutanes: Access to Cyclohexenones with Quaternary Stereogenic Centers

(2008) Tobias Seiser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biomimetic Carbene-Catalyzed Oxidations of Aldehydes Using TEMPO

(2008) Joyram Guin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in carbon–carbon bond-forming reactions involving homoenolates generated by NHC catalysis

(2008) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

Nucleophilic Carbene Catalyzed Synthesis of 1,2 Amino Alcohols Via Azidation of Epoxy Aldehydes

(2008) Harit U. Vora et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Asymmetric Intermolecular Stetter Reaction of Glyoxamides with Alkylidenemalonates

(2008) Qin Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lewis Acid−Lewis Base Catalyzed Enantioselective Hetero-Diels−Alder Reaction for Direct Access to δ-Lactones

(2008) Paolo S. Tiseni et al.   ORGANIC LETTERS