Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy
Authors
Keywords
-
Journal
Nature Communications
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2015-03-10
DOI
10.1038/ncomms7496
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- BRD7 Regulates XBP1s’ Activity and Glucose Homeostasis through Its Interaction with the Regulatory Subunits of PI3K
- (2014) Sang Won Park et al. Cell Metabolism
- Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance
- (2014) Xuefei Tian et al. JOURNAL OF CLINICAL INVESTIGATION
- Molecular mechanisms of diabetic kidney disease
- (2014) Kimberly Reidy et al. JOURNAL OF CLINICAL INVESTIGATION
- Long-Term Treatment with the Sodium Glucose Cotransporter 2 Inhibitor, Dapagliflozin, Ameliorates Glucose Homeostasis and Diabetic Nephropathy in db/db Mice
- (2014) Naoto Terami et al. PLoS One
- In vivo imaging of kidney glomeruli transplanted into the anterior chamber of the mouse eye
- (2014) Andreas D. Kistler et al. Scientific Reports
- Relationship between chronic kidney disease and metabolic syndrome: current perspectives
- (2014) Khaled Nashar et al. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
- Hyperglycemia Promotes Myelopoiesis and Impairs the Resolution of Atherosclerosis
- (2013) Prabhakara R. Nagareddy et al. Cell Metabolism
- X-Box Binding Protein 1 Is Essential for Insulin Regulation of Pancreatic -Cell Function
- (2013) M. Akiyama et al. DIABETES
- ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
- (2013) Jaeseok Han et al. NATURE CELL BIOLOGY
- Endoplasmic Reticulum Stress and Type 2 Diabetes
- (2012) Sung Hoon Back et al. Annual Review of Biochemistry
- Selective Insulin and Leptin Resistance in Metabolic Disorders
- (2012) A. Christine Könner et al. Cell Metabolism
- The insulin receptor and the kidney
- (2012) Lorna J. Hale et al. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- Diabetic nephropathy in type 1 diabetes: has the outlook improved since the 1980s?
- (2012) S. M. Marshall DIABETOLOGIA
- The impact of the unfolded protein response on human disease
- (2012) Shiyu Wang et al. JOURNAL OF CELL BIOLOGY
- Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc
- (2012) F. Bock et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Low but sustained coagulation activation ameliorates glucose-induced podocyte apoptosis: protective effect of factor V Leiden in diabetic nephropathy
- (2011) H. Wang et al. BLOOD
- Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes
- (2011) T. Madhusudhan et al. BLOOD
- Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-out Mice
- (2011) Michael J. Jurczak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nuclear Factor Erythroid-derived 2 (Nfe2) Regulates JunD DNA-binding Activity via Acetylation
- (2011) Muhammed Kashif et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of mTOR in podocyte function and diabetic nephropathy in humans and mice
- (2011) Markus Gödel et al. JOURNAL OF CLINICAL INVESTIGATION
- Risk for ESRD in Type 1 Diabetes Remains High Despite Renoprotection
- (2011) E. T. Rosolowsky et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Stressed out about obesity: IRE1α–XBP1 in metabolic disorders
- (2011) Haibo Sha et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Endoplasmic reticulum stress, obesity and diabetes
- (2011) Miriam Cnop et al. TRENDS IN MOLECULAR MEDICINE
- Induction of Diabetes in Aged C57B6 Mice Results in Severe Nephropathy
- (2010) Jin Wu et al. AMERICAN JOURNAL OF PATHOLOGY
- Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function
- (2010) Gavin I. Welsh et al. Cell Metabolism
- Endoplasmic reticulum stress as a progression factor for kidney injury
- (2010) Reiko Inagi CURRENT OPINION IN PHARMACOLOGY
- Tauroursodeoxycholic Acid May Improve Liver and Muscle but Not Adipose Tissue Insulin Sensitivity in Obese Men and Women
- (2010) Marleen Kars et al. DIABETES
- Attenuation of diabetic nephropathy in diabetes rats induced by streptozotocin by regulating the endoplasmic reticulum stress inflammatory response
- (2010) Wei Qi et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
- (2010) Fabio Martinon et al. NATURE IMMUNOLOGY
- A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box–binding protein-1 to modulate the unfolded protein response
- (2010) Jonathon N Winnay et al. NATURE MEDICINE
- The regulatory subunits of PI3K, p85α and p85β, interact with XBP-1 and increase its nuclear translocation
- (2010) Sang Won Park et al. NATURE MEDICINE
- XBP1: the last two decades
- (2009) L H Glimcher ANNALS OF THE RHEUMATIC DISEASES
- XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease
- (2008) Arthur Kaser et al. CELL
- Is the ER Stressed out in Diabetic Kidney Disease?
- (2008) F. C. Brosius et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Proteinuria and Hyperglycemia Induce Endoplasmic Reticulum Stress
- (2008) M. T. Lindenmeyer et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started