Reduced Tyk2 gene expression in β-cells due to natural mutation determines susceptibility to virus-induced diabetes

Virus Infections in Type 1 Diabetes

(2013) K. T. Coppieters et al.   Cold Spring Harbor Perspectives in Medicine

Pathology: Cause and effect

(2012) Erika Jonietz   NATURE

Diabetes in numbers

(2012) Tony Scully   NATURE

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

(2012) L. Sun et al.   SCIENCE

RNA sensor–induced type I IFN prevents diabetes caused by a β cell–tropic virus in mice

(2011) Stephen A. McCartney et al.   JOURNAL OF CLINICAL INVESTIGATION

Enteroviruses in the pathogenesis of type 1 diabetes

(2010) Sisko Tauriainen et al.   Seminars in Immunopathology

Enterovirus Infection, CXC Chemokine Ligand 10 (CXCL10), and CXCR3 Circuit: A Mechanism of Accelerated  -Cell Failure in Fulminant Type 1 Diabetes

(2009) S. Tanaka et al.   DIABETES

Single pancreatic beta cells co-express multiple islet hormone genes in mice

(2009) H. Katsuta et al.   DIABETOLOGIA

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

(2009) Hiroki Ishikawa et al.   NATURE

Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes

(2009) S. Nejentsev et al.   SCIENCE

The significance of T cells, B cells, antibodies and macrophages against encephalomyocarditis (EMC)-D virus-induced diabetes in mice

(2008) Etsushi Kounoue et al.   ARCHIVES OF VIROLOGY

Innate immunity to virus infection

(2008) Osamu Takeuchi et al.   IMMUNOLOGICAL REVIEWS