Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation

Rac1-dependent recruitment of PAK2 to G2phase centrosomes and their roles in the regulation of mitotic entry

(2014) Martin May et al.   CELL CYCLE

The Cep192-Organized Aurora A-Plk1 Cascade Is Essential for Centrosome Cycle and Bipolar Spindle Assembly

(2014) Vladimir Joukov et al.   MOLECULAR CELL

Mechanisms Underlying Plk1 Polo-Box Domain-Mediated Biological Processes and Their Physiological Significance

(2014) Kyung S. Lee et al.   MOLECULES AND CELLS

Balanced Activity of Three Mitotic Motors Is Required for Bipolar Spindle Assembly and Chromosome Segregation

(2014) Roy G.H.P. van Heesbeen et al.   Cell Reports

Kinesin-5: Cross-bridging mechanism to targeted clinical therapy

(2013) Edward J. Wojcik et al.   GENE

FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas

(2013) Silvia Licciulli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P21-Activated Kinase 1 (PAK1) as a Therapeutic Target in BRAF Wild-Type Melanoma

(2013) Christy C. Ong et al.   JNCI-Journal of the National Cancer Institute

p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model

(2012) H. Y. Chow et al.   CANCER RESEARCH

Signaling-dependent Phosphorylation of Mitotic Centromere-associated Kinesin Regulates Microtubule Depolymerization and Its Centrosomal Localization

(2012) Suresh B. Pakala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell–cell junctions by differentially regulating Tiam1 activity

(2012) Natalie A. Mack et al.   NATURE CELL BIOLOGY

Plk1 Controls the Nek2A-PP1γ Antagonism in Centrosome Disjunction

(2011) Balca R. Mardin et al.   CURRENT BIOLOGY

Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1

(2011) Ewan Smith et al.   EMBO JOURNAL

Nek9 is a Plk1-activated kinase that controls early centrosome separation through Nek6/7 and Eg5

(2011) M Teresa Bertran et al.   EMBO JOURNAL

Tiam1-Rac Signaling Counteracts Eg5 during Bipolar Spindle Assembly to Facilitate Chromosome Congression

(2010) Simon A. Woodcock et al.   CURRENT BIOLOGY

Mechanisms of Centrosome Separation and Bipolar Spindle Assembly

(2010) Marvin E. Tanenbaum et al.   DEVELOPMENTAL CELL

Activation of cyclin B1–Cdk1 synchronizes events in the nucleus and the cytoplasm at mitosis

(2010) Olivier Gavet et al.   JOURNAL OF CELL BIOLOGY

Mitotic functions of kinesin-5

(2010) Nick P. Ferenz et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Interplay of Microtubule Dynamics and Sliding during Bipolar Spindle Formation in Mammalian Cells

(2009) Swapna Kollu et al.   CURRENT BIOLOGY

The decision to enter mitosis: feedback and redundancy in the mitotic entry network

(2009) Arne Lindqvist et al.   JOURNAL OF CELL BIOLOGY

A Modified Tandem Affinity Purification Technique Identifies That 14-3-3 Proteins Interact with Tiam1, an Interaction Which Controls Tiam1 Stability

(2009) Simon A. Woodcock et al.   JOURNAL OF PROTEOME RESEARCH

Src-Induced Disassembly of Adherens Junctions Requires Localized Phosphorylation and Degradation of the Rac Activator Tiam1

(2009) Simon A. Woodcock et al.   MOLECULAR CELL

Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly

(2008) Marvin E Tanenbaum et al.   EMBO JOURNAL

P21-activated kinase is required for mitotic progression and regulates Plk1

(2008) B Maroto et al.   ONCOGENE