Two enzymes with redundant fructose bisphosphatase activity sustain gluconeogenesis and virulence in Mycobacterium tuberculosis

Methylcitrate cycle defines the bactericidal essentiality of isocitrate lyase for survival ofMycobacterium tuberculosison fatty acids

(2014) Hyungjin Eoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Triosephosphate Isomerase Is Dispensable In Vitro yet Essential for Mycobacterium tuberculosis To Establish Infection

(2014) C. Trujillo et al.   mBio

Inactivation of Fructose-1,6-Bisphosphate Aldolase Prevents Optimal Co-catabolism of Glycolytic and Gluconeogenic Carbon Substrates in Mycobacterium tuberculosis

(2014) Susan Puckett et al.   PLoS Pathogens

A Hidden Markov Model for identifying essential and growth-defect regions in bacterial genomes from transposon insertion sequencing data

(2013) Michael A DeJesus et al.   BMC BIOINFORMATICS

Multifunctional essentiality of succinate metabolism in adaptation to hypoxia in Mycobacterium tuberculosis

(2013) H. Eoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucose Phosphorylation Is Required for Mycobacterium tuberculosis Persistence in Mice

(2013) Joeli Marrero et al.   PLoS Pathogens

glpX Gene of Mycobacterium tuberculosis: Heterologous Expression, Purification, and Enzymatic Characterization of the Encoded Fructose 1,6-bisphosphatase II

(2011) Hiten J. Gutka et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Riboneogenesis in Yeast

(2011) Michelle F. Clasquin et al.   CELL

Glycolytic and Non-glycolytic Functions ofMycobacterium tuberculosisFructose-1,6-bisphosphate Aldolase, an Essential Enzyme Produced by Replicating and Non-replicating Bacilli

(2011) Maria de la Paz Santangelo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase

(2011) Juan Du et al.   NATURE

Structural basis for the bifunctionality of fructose-1,6-bisphosphate aldolase/phosphatase

(2011) Shinya Fushinobu et al.   NATURE

13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation

(2011) Dany J. V. Beste et al.   PLoS Pathogens

Metabolomics of Mycobacterium tuberculosis Reveals Compartmentalized Co-Catabolism of Carbon Substrates

(2010) Luiz Pedro S. de Carvalho et al.   CHEMISTRY & BIOLOGY

Structure and Activity of the Metal-independent Fructose-1,6-bisphosphatase YK23 fromSaccharomyces cerevisiae

(2010) Ekaterina Kuznetsova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fructose 1,6-bisphosphate aldolase/phosphatase may be an ancestral gluconeogenic enzyme

(2010) Rafael F. Say et al.   NATURE

Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection

(2010) J. Marrero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Bacillus subtilis ywjI (glpX) Gene Encodes a Class II Fructose-1,6-Bisphosphatase, Functionally Equivalent to the Class III Fbp Enzyme

(2009) M. Jules et al.   JOURNAL OF BACTERIOLOGY

Phosphate Depletion: A Novel Trigger forMycobacterium tuberculosisPersistence

(2009) Dalin Rifat et al.   JOURNAL OF INFECTIOUS DISEASES

Systematic phenome analysis of Escherichia coli multiple-knockout mutants reveals hidden reactions in central carbon metabolism

(2009) Kenji Nakahigashi et al.   Molecular Systems Biology

Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

(2009) Bryson D Bennett et al.   Nature Chemical Biology

The Genetic Requirements for Fast and Slow Growth in Mycobacteria

(2009) Dany J. V. Beste et al.   PLoS One

The histidine phosphatase superfamily: structure and function

(2008) Daniel J. Rigden   BIOCHEMICAL JOURNAL

Rv2131c fromMycobacterium tuberculosisIs a CysQ 3′-Phosphoadenosine-5′-phosphatase†

(2008) Stavroula K. Hatzios et al.   BIOCHEMISTRY

The Gluconeogenic Enzyme Fructose-1,6-Bisphosphatase Is Dispensable for Growth of the YeastYarrowia lipolyticain Gluconeogenic Substrates

(2008) Raquel Jardón et al.   EUKARYOTIC CELL

Carbon Catabolite Repression in Bacillus subtilis: Quantitative Analysis of Repression Exerted by Different Carbon Sources

(2008) K. D. Singh et al.   JOURNAL OF BACTERIOLOGY

Structural and Biochemical Characterization of the Type II Fructose-1,6-bisphosphatase GlpX fromEscherichia coli

(2008) Greg Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY