Optodynamic simulation of β-adrenergic receptor signalling

Minireview: More Than Just a Hammer: Ligand “Bias” and Pharmaceutical Discovery

(2014) Louis M. Luttrell   MOLECULAR ENDOCRINOLOGY

Amygdala interneuron subtypes control fear learning through disinhibition

(2014) Steffen B. E. Wolff et al.   NATURE

Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis

(2014) Nikoleta G Tsvetanova et al.   Nature Chemical Biology

Targeting cells with single vectors using multiple-feature Boolean logic

(2014) Lief E Fenno et al.   NATURE METHODS

Conformational biosensors reveal GPCR signalling from endosomes

(2013) Roshanak Irannejad et al.   NATURE

Fabrication and application of flexible, multimodal light-emitting devices for wireless optogenetics

(2013) Jordan G McCall et al.   Nature Protocols

Signalling bias in new drug discovery: detection, quantification and therapeutic impact

(2013) Terry Kenakin et al.   NATURE REVIEWS DRUG DISCOVERY

Injectable, Cellular-Scale Optoelectronics with Applications for Wireless Optogenetics

(2013) T.-i. Kim et al.   SCIENCE

Serine 363 Is Required for Nociceptin/Orphanin FQ Opioid Receptor (NOPR) Desensitization, Internalization, and Arrestin Signaling

(2012) Nancy R. Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optogenetic investigation of neural circuits underlying brain disease in animal models

(2012) Kay M. Tye et al.   NATURE REVIEWS NEUROSCIENCE

Reproducible and Sustained Regulation of Gαs Signalling Using a Metazoan Opsin as an Optogenetic Tool

(2012) Helena J. Bailes et al.   PLoS One

Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones

(2011) Alex Straiker et al.   BRITISH JOURNAL OF PHARMACOLOGY

Construction of implantable optical fibers for long-term optogenetic manipulation of neural circuits

(2011) Dennis R Sparta et al.   Nature Protocols

Selective p38α MAPK Deletion in Serotonergic Neurons Produces Stress Resilience in Models of Depression and Addiction

(2011) Michael R. Bruchas et al.   NEURON

Distinct Phosphorylation Sites on the  2-Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of  -Arrestin

(2011) K. N. Nobles et al.   Science Signaling

Substitution of 5-HT1AReceptor Signaling by a Light-activated G Protein-coupled Receptor

(2010) Eugene Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Interneurons in the basolateral amygdala

(2010) Jay Spampanato et al.   NEUROPHARMACOLOGY

Beyond Desensitization: Physiological Relevance of Arrestin-Dependent Signaling

(2010) L. M. Luttrell et al.   PHARMACOLOGICAL REVIEWS

Kinase cascades and ligand-directed signaling at the kappa opioid receptor

(2010) Michael R. Bruchas et al.   PSYCHOPHARMACOLOGY

Therapeutic potential of β-arrestin- and G protein-biased agonists

(2010) Erin J. Whalen et al.   TRENDS IN MOLECULAR MEDICINE

Temporally precise in vivo control of intracellular signalling

(2009) Raag D. Airan et al.   NATURE

Endocytosis and signalling: intertwining molecular networks

(2009) Alexander Sorkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Amygdala Inhibitory Circuits and the Control of Fear Memory

(2009) Ingrid Ehrlich et al.   NEURON

Dual Role of the β2-Adrenergic Receptor C Terminus for the Binding of β-Arrestin and Receptor Internalization

(2008) Cornelius Krasel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid CB1 cannabinoid receptor desensitization defines the time course of ERK1/2 MAP kinase signaling

(2007) Tanya L. Daigle et al.   NEUROPHARMACOLOGY