Journal
PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
Volume 465, Issue 2109, Pages 2751-2759Publisher
ROYAL SOC
DOI: 10.1098/rspa.2009.0181
Keywords
nanoparticles; conjugated polymers; biological labelling
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Funding
- King's College London
- Royal Society
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The use of nanoparticles in biology, especially in cellular imaging, is extremely promising and offers numerous advantages over existing organic dye systems. There are, however, constraints that need to be addressed before the use of such materials in mainstream clinical applications can be realized. One of the main concerns is the use of metal-containing particles that are potentially toxic or interfere with other diagnostic processes. Here, we present the use of simple conjugated polymer nanoparticles as alternative photostable cellular optical imaging agents.
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