Structural basis and distal effects of Gag substrate coevolution in drug resistance to HIV-1 protease
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Title
Structural basis and distal effects of Gag substrate coevolution in drug resistance to HIV-1 protease
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 111, Issue 45, Pages 15993-15998
Publisher
Proceedings of the National Academy of Sciences
Online
2014-10-30
DOI
10.1073/pnas.1414063111
References
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Related references
Note: Only part of the references are listed.- HIV-1 Protease-Substrate Coevolution in Nelfinavir Resistance
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- Efflux-Mediated Drug Resistance in Bacteria
- (2009) Xian-Zhi Li et al. DRUGS
- Human Immunodeficiency Virus Type 1 Protease-Correlated Cleavage Site Mutations Enhance Inhibitor Resistance
- (2009) M. Kolli et al. JOURNAL OF VIROLOGY
- Factors underlying sensitivity of cancers to small-molecule kinase inhibitors
- (2009) Pasi A. Jänne et al. NATURE REVIEWS DRUG DISCOVERY
- Gag Mutations Strongly Contribute to HIV-1 Resistance to Protease Inhibitors in Highly Drug-Experienced Patients besides Compensating for Fitness Loss
- (2009) Elisabeth Dam et al. PLoS Pathogens
- Effect of the Active Site D25N Mutation on the Structure, Stability, and Ligand Binding of the Mature HIV-1 Protease
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- The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
- (2008) C.-H. Yun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rapid structural fluctuations of the free HIV protease flaps in solution: Relationship to crystal structures and comparison with predictions of dynamics calculations
- (2002) Darón I. Freedberg et al. PROTEIN SCIENCE
- Lack of synergy for inhibitors targeting a multi-drug-resistant HIV-1 protease
- (2002) Nancy M. King et al. PROTEIN SCIENCE
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