Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA

Distal Structural Elements Coordinate a Conserved Base Flipping Network

(2013) Douglas M. Matje et al.   BIOCHEMISTRY

Aminoglycosides

(2013) Justin Jackson et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Exogenously acquired 16S rRNA methyltransferases found in aminoglycoside-resistant pathogenic Gram-negative bacteria: An update

(2012) Jun-ichi Wachino et al.   DRUG RESISTANCE UPDATES

Correlation Between Upstream Human Activities and Riverine Antibiotic Resistance Genes

(2012) Amy Pruden et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Graphical tools for macromolecular crystallography inPHENIX

(2012) Nathaniel Echols et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Structural Insights into Methyltransferase KsgA Function in 30S Ribosomal Subunit Biogenesis

(2012) Daniel Boehringer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MODOMICS: a database of RNA modification pathways—2013 update

(2012) Magdalena A. Machnicka et al.   NUCLEIC ACIDS RESEARCH

Antibiotic resistance is ancient

(2011) Vanessa M. D’Costa et al.   NATURE

Integration, scaling, space-group assignment and post-refinement

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Aminoglycoside modifying enzymes

(2010) Maria S. Ramirez et al.   DRUG RESISTANCE UPDATES

Call of the wild: antibiotic resistance genes in natural environments

(2010) Heather K. Allen et al.   NATURE REVIEWS MICROBIOLOGY

Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m 7 G methyltransferases

(2010) Nilofer Husain et al.   NUCLEIC ACIDS RESEARCH

Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria

(2010) Rachel Macmaster et al.   NUCLEIC ACIDS RESEARCH

Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit

(2010) Nilofer Husain et al.   NUCLEIC ACIDS RESEARCH

Expression, purification and crystallization of adenosine 1408 aminoglycoside-resistance rRNA methyltransferases for structural studies

(2010) Natalia Zelinskaya et al.   PROTEIN EXPRESSION AND PURIFICATION

The aminoglycoside resistance methyltransferases from the ArmA/Rmt family operate late in the 30S ribosomal biogenesis pathway

(2010) T. Zarubica et al.   RNA

Structural Bases for 16 S rRNA Methylation Catalyzed by ArmA and RmtB Methyltransferases

(2009) Emmanuelle Schmitt et al.   JOURNAL OF MOLECULAR BIOLOGY

Determination of the target nucleosides for members of two families of 16S rRNA methyltransferases that confer resistance to partially overlapping groups of aminoglycoside antibiotics

(2009) M. Savic et al.   NUCLEIC ACIDS RESEARCH

Potential of old-generation antibiotics to address current need for new antibiotics

(2008) Matthew E Falagas et al.   Expert Review of Anti-Infective Therapy

A conserved rRNA methyltransferase regulates ribosome biogenesis

(2008) Zhili Xu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY