Restoration of visual function by expression of a light-gated mammalian ion channel in retinal ganglion cells or ON-bipolar cells

Differential responses to high-frequency electrical stimulation in ON and OFF retinal ganglion cells

(2014) Perry Twyford et al.   Journal of Neural Engineering

Tethered ligands reveal glutamate receptor desensitization depends on subunit occupancy

(2014) Andreas Reiner et al.   Nature Chemical Biology

Restoring Visual Function to Blind Mice with a Photoswitch that Exploits Electrophysiological Remodeling of Retinal Ganglion Cells

(2014) Ivan Tochitsky et al.   NEURON

Canine Retina Has a Primate Fovea-Like Bouquet of Cone Photoreceptors Which Is Affected by Inherited Macular Degenerations

(2014) William A. Beltran et al.   PLoS One

A Red-Shifted, Fast-Relaxing Azobenzene Photoswitch for Visible Light Control of an Ionotropic Glutamate Receptor

(2013) Michael A. Kienzler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Optical control of metabotropic glutamate receptors

(2013) Joshua Levitz et al.   NATURE NEUROSCIENCE

Optochemical control of genetically engineered neuronal nicotinic acetylcholine receptors

(2012) Ivan Tochitsky et al.   Nature Chemistry

Optical Control of Endogenous Proteins with a Photoswitchable Conditional Subunit Reveals a Role for TREK1 in GABAB Signaling

(2012) Guillaume Sandoz et al.   NEURON

Photochemical Restoration of Visual Responses in Blind Mice

(2012) Aleksandra Polosukhina et al.   NEURON

Interim Results from the International Trial of Second Sight's Visual Prosthesis

(2012) Mark S. Humayun et al.   OPHTHALMOLOGY

Retinal prosthetic strategy with the capacity to restore normal vision

(2012) S. Nirenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optogenetic approaches to restoring visual function in retinitis pigmentosa

(2011) Volker Busskamp et al.   CURRENT OPINION IN NEUROBIOLOGY

Optogenetic therapy for retinitis pigmentosa

(2011) V Busskamp et al.   GENE THERAPY

LiGluR Restores Visual Responses in Rodent Models of Inherited Blindness

(2011) Natalia Caporale et al.   MOLECULAR THERAPY

Virally delivered Channelrhodopsin-2 Safely and Effectively Restores Visual Function in Multiple Mouse Models of Blindness

(2011) M Mehdi Doroudchi et al.   MOLECULAR THERAPY

Visual Function in Mice with Photoreceptor Degeneration and Transgenic Expression of Channelrhodopsin 2 in Ganglion Cells

(2010) S. Thyagarajan et al.   JOURNAL OF NEUROSCIENCE

Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina

(2010) Hilda Petrs-Silva et al.   MOLECULAR THERAPY

Subretinal electronic chips allow blind patients to read letters and combine them to words

(2010) E. Zrenner et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa

(2010) V. Busskamp et al.   SCIENCE

Rod-Derived Cone Viability Factor for Treating Blinding Diseases: From Clinic to Redox Signaling

(2010) T. Leveillard et al.   Science Translational Medicine

Cone Contacts, Mosaics, and Territories of Bipolar Cells in the Mouse Retina

(2009) H. Wassle et al.   JOURNAL OF NEUROSCIENCE

The use of canine models of inherited retinal degeneration to test novel therapeutic approaches

(2009) William A. Beltran   VETERINARY OPHTHALMOLOGY

Review and update: Current treatment trends for patients with retinitis pigmentosa

(2009) Kelly Shintani et al.   OPTOMETRY

Retinal Ganglion Cells Survive and Maintain Normal Dendritic Morphology in a Mouse Model of Inherited Photoreceptor Degeneration

(2008) F. Mazzoni et al.   JOURNAL OF NEUROSCIENCE

Photoreceptor Cell Death Mechanisms in Inherited Retinal Degeneration

(2008) Javier Sancho-Pelluz et al.   MOLECULAR NEUROBIOLOGY

Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration

(2008) Pamela S Lagali et al.   NATURE NEUROSCIENCE

Restoration of visual function in retinal degeneration mice by ectopic expression of melanopsin

(2008) B. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA