Utilization of extracellular information before ligand-receptor binding reaches equilibrium expands and shifts the input dynamic range

Inhibitory GEF Phosphorylation Provides Negative Feedback in the Yeast Polarity Circuit

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Parts-per-Million of Polyethylene Glycol as a Non-Interfering Blocking Agent for Homogeneous Biosensor Development

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Quantitative Measurement of Protein Relocalization in Live Cells

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A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum

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Beyond symmetry-breaking: competition and negative feedback in GTPase regulation

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Negative auto-regulation increases the input dynamic-range of the arabinose system of Escherichia coli

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Responding to chemical gradients: bacterial chemotaxis

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Improved readout precision of the Bicoid morphogen gradient by early decoding

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Disentangling signaling gradients generated by equivalent sources

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Eukaryotic Chemotaxis: A Network of Signaling Pathways Controls Motility, Directional Sensing, and Polarity

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Functional Motifs in Biochemical Reaction Networks

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Ligand Depletion in vivo Modulates the Dynamic Range and Cooperativity of Signal Transduction

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Covering a Broad Dynamic Range: Information Processing at the Erythropoietin Receptor

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Detailed Simulations of Cell Biology with Smoldyn 2.1

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Defining Network Topologies that Can Achieve Biochemical Adaptation

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Systems biology: model based evaluation and comparison of potential explanations for given biological data

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Negative autoregulation linearizes the dose-response and suppresses the heterogeneity of gene expression

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Symmetry Breaking in Biology

(2009) R. Li et al.   Cold Spring Harbor Perspectives in Biology

Symmetry Breaking in the Life Cycle of the Budding Yeast

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Chemical Gradients and Chemotropism in Yeast

(2009) R. A. Arkowitz   Cold Spring Harbor Perspectives in Biology

On the spontaneous emergence of cell polarity

(2008) Steven J. Altschuler et al.   NATURE

Negative feedback that improves information transmission in yeast signalling

(2008) Richard C. Yu et al.   NATURE

Robust Spatial Sensing of Mating Pheromone Gradients by Yeast Cells

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Dose-to-Duration Encoding and Signaling beyond Saturation in Intracellular Signaling Networks

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