Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1

Toward rationally redesigning bacterial two-component signaling systems using coevolutionary information

(2014) Ryan R. Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+homeostasis

(2013) Sandra E. Wiley et al.   EMBO Molecular Medicine

Nutrient-Deprivation Autophagy Factor-1 (NAF-1): Biochemical Properties of a Novel Cellular Target for Anti-Diabetic Drugs

(2013) Sagi Tamir et al.   PLoS One

NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth

(2013) Yang-Sung Sohn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distal Loop Flexibility of a Regulatory Domain Modulates Dynamics and Activity of C-Terminal Src Kinase (Csk)

(2013) Sulyman Barkho et al.   PLoS Computational Biology

Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance

(2012) Ahmed F. Salem et al.   CELL CYCLE

Bcl-2-associated autophagy regulator Naf-1 required for maintenance of skeletal muscle

(2012) N. C. Chang et al.   HUMAN MOLECULAR GENETICS

Dynamic Structural Changes Are Observed upon Collagen and Metal Ion Binding to the Integrin α1 I Domain

(2012) Paul H. Weinreb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NADPH Inhibits [2Fe-2S] Cluster Protein Transfer from Diabetes Drug Target MitoNEET to an Apo-acceptor Protein

(2012) John A. Zuris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of Arabidopsis NEET Reveals an Ancient Role for NEET Proteins in Iron Metabolism

(2012) R. Nechushtai et al.   PLANT CELL

Regulation of the Autophagic Bcl-2/Beclin 1 Interaction

(2012) Jean-Paul Decuypere et al.   Cells

Studying protein–protein interactions using peptide arrays

(2011) Chen Katz et al.   CHEMICAL SOCIETY REVIEWS

Direct-coupling analysis of residue coevolution captures native contacts across many protein families

(2011) F. Morcos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1

(2009) Natasha C Chang et al.   EMBO JOURNAL

Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice

(2009) Y.-F. Chen et al.   GENES & DEVELOPMENT

Pro-interleukin (IL)-1β Shares a Core Region of Stability as Compared with Mature IL-1β While Maintaining a Distinctly Different Configurational Landscape

(2009) Kendra L. Hailey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Miner1: The Redox-active 2Fe-2S Protein Causative in Wolfram Syndrome 2

(2009) Andrea R. Conlan et al.   JOURNAL OF MOLECULAR BIOLOGY

High-resolution protein complexes from integrating genomic information with molecular simulation

(2009) Alexander Schug et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Structure and Interactions of the Proline-rich Domain of ASPP2

(2008) Shahar Rotem et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY