XAF1 directs apoptotic switch of p53 signaling through activation of HIPK2 and ZNF313

ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21WAF1

(2013) J Han et al.   CELL DEATH AND DIFFERENTIATION

A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer

(2013) Andrea Lunardi et al.   NATURE GENETICS

p21WAF1 and tumourigenesis

(2012) Noel A. Warfel et al.   CURRENT OPINION IN ONCOLOGY

XIAP-associated factor 1 (XAF1), a novel target of p53, enhances p53-mediated apoptosis via post-translational modification

(2011) Bing Zou et al.   MOLECULAR CARCINOGENESIS

Tumor suppressor XIAP-Associated factor 1 (XAF1) cooperates with tumor necrosis factor-related apoptosis-inducing ligand to suppress colon cancer growth and trigger tumor regression

(2010) Shui Ping Tu et al.   CANCER

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

How cells switch HIPK2 on and off

(2008) D Sombroek et al.   CELL DEATH AND DIFFERENTIATION

Interactions between XIAP Associated Factor 1 and a Nuclear Co-Activator, CBP, in Colon Cancer Cells

(2008) Yunwei Sun et al.   DIGESTION

Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR

(2008) Melanie Winter et al.   NATURE CELL BIOLOGY

An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response

(2008) Marco A. Calzado et al.   NATURE CELL BIOLOGY

A complex barcode underlies the heterogeneous response of p53 to stress

(2008) Fiona Murray-Zmijewski et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY