Synthetic genetic array screen identifies PP2A as a therapeutic target in Mad2-overexpressing tumors
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Synthetic genetic array screen identifies PP2A as a therapeutic target in Mad2-overexpressing tumors
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 111, Issue 4, Pages 1628-1633
Publisher
Proceedings of the National Academy of Sciences
Online
2014-01-15
DOI
10.1073/pnas.1315588111
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer
- (2013) Parthasarathy Seshacharyulu et al. CANCER LETTERS
- Checkpoint-Independent Stabilization of Kinetochore-Microtubule Attachments by Mad2 in Human Cells
- (2012) Lilian Kabeche et al. CURRENT BIOLOGY
- Synthesis and anticancer activity of a series of norcantharidin analogues
- (2012) Mark Tarleton et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- PP2A holoenzymes negatively and positively regulate cell cycle progression by dephosphorylating pocket proteins and multiple CDK substrates
- (2012) Alison Kurimchak et al. GENE
- Novel Checkpoint Pathway Organization Promotes Genome Stability in Stationary-Phase Yeast Cells
- (2012) B. Alver et al. MOLECULAR AND CELLULAR BIOLOGY
- What Evidence Is There for the Homology of Protein-Protein Interactions?
- (2012) Anna C. F. Lewis et al. PLoS Computational Biology
- Mad2 Is a Critical Mediator of the Chromosome Instability Observed upon Rb and p53 Pathway Inhibition
- (2011) Juan-Manuel Schvartzman et al. CANCER CELL
- Kinetochores and disease: keeping microtubule dynamics in check!
- (2011) Samuel F Bakhoum et al. CURRENT OPINION IN CELL BIOLOGY
- Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas
- (2011) Melissa K McConechy et al. JOURNAL OF PATHOLOGY
- Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase
- (2011) Emily A. Foley et al. NATURE CELL BIOLOGY
- Mitotic arrest defective protein 2 expression abnormality and its clinicopathologic significance in human osteosarcoma
- (2010) LING YU et al. APMIS
- Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis
- (2010) Wei Li et al. CANCER SCIENCE
- Mechanisms of Chromosomal Instability
- (2010) Sarah L. Thompson et al. CURRENT BIOLOGY
- Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal
- (2010) Rocio Sotillo et al. NATURE
- Live-cell imaging RNAi screen identifies PP2A–B55α and importin-β1 as key mitotic exit regulators in human cells
- (2010) Michael H. A. Schmitz et al. NATURE CELL BIOLOGY
- Phosphorylation of the spindle checkpoint protein Mad2 regulates its conformational transition
- (2010) S. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma
- (2010) Siân Jones et al. SCIENCE
- Systematic Analysis of Human Protein Complexes Identifies Chromosome Segregation Proteins
- (2010) J. R. A. Hutchins et al. SCIENCE
- Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms
- (2009) Jie Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genome stability is ensured by temporal control of kinetochore–microtubule dynamics
- (2008) Samuel F. Bakhoum et al. NATURE CELL BIOLOGY
- EB1 promotes Aurora-B kinase activity through blocking its inactivation by protein phosphatase 2A
- (2008) L. Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started