UNC93B1 is essential for the plasma membrane localization and signaling of Toll-like receptor 5

Acidic Amino Acid Residues in the Juxtamembrane Region of the Nucleotide-Sensing TLRs Are Important for UNC93B1 Binding and Signaling

(2013) J. Kim et al.   JOURNAL OF IMMUNOLOGY

An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing

(2013) Masahiro Onji et al.   Nature Communications

UNC93B1 mediates differential trafficking of endosomal TLRs

(2013) Bettina L Lee et al.   eLife

Recognition of Profilin by Toll-like Receptor 12 Is Critical for Host Resistance to Toxoplasma gondii

(2012) A. Alicia Koblansky et al.   IMMUNITY

PRAT4A-dependent expression of cell surface TLR5 on neutrophils, classical monocytes and dendritic cells

(2012) T. Shibata et al.   INTERNATIONAL IMMUNOLOGY

The Role of UNC93B1 Protein in Surface Localization of TLR3 Receptor and in Cell Priming to Nucleic Acid Agonists

(2012) Jelka Pohar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleosome-induced neutrophil activation occurs independently of TLR9 and endosomal acidification: Implications for systemic lupus erythematosus

(2011) Dennis Lindau et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Transmembrane Mutations in Toll-like Receptor 9 Bypass the Requirement for Ectodomain Proteolysis and Induce Fatal Inflammation

(2011) Maria L. Mouchess et al.   IMMUNITY

UNC93B1 Physically Associates with Human TLR8 and Regulates TLR8-Mediated Signaling

(2011) Hiroki Itoh et al.   PLoS One

TLR5 functions as an endocytic receptor to enhance flagellin-specific adaptive immunity

(2010) Shirdi E. Letran et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

UNC93B1 Is Essential for TLR11 Activation and IL-12-dependent Host Resistance toToxoplasma gondii

(2010) Reed Pifer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing

(2009) Ryutaro Fukui et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulatory molecules required for nucleotide-sensing Toll-like receptors

(2008) Shin-Ichiroh Saitoh et al.   IMMUNOLOGICAL REVIEWS

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

(2008) You-Me Kim et al.   NATURE

Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5

(2008) Satoshi Uematsu et al.   NATURE IMMUNOLOGY

An Agonist of Toll-Like Receptor 5 Has Radioprotective Activity in Mouse and Primate Models

(2008) L. G. Burdelya et al.   SCIENCE