Human mutations in methylenetetrahydrofolate dehydrogenase 1 impair nuclear de novo thymidylate biosynthesis

Nuclear Enrichment of Folate Cofactors and Methylenetetrahydrofolate Dehydrogenase 1 (MTHFD1) Protectde NovoThymidylate Biosynthesis during Folate Deficiency

(2014) Martha S. Field et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Severe Combined Immunodeficiency Resulting From Mutations in MTHFD1

(2013) M. D. Keller et al.   PEDIATRICS

From Murine to Human Nude/SCID: The Thymus, T-Cell Development and the Missing Link

(2012) Rosa Romano et al.   Clinical & Developmental Immunology

Serine Hydroxymethyltransferase Anchorsde NovoThymidylate Synthesis Pathway to Nuclear Lamina for DNA Synthesis

(2012) Donald D. Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced MTHFD1 Activity in Male Mice Perturbs Folate- and Choline-Dependent One-Carbon Metabolism as Well as Transsulfuration

(2012) Martha S. Field et al.   JOURNAL OF NUTRITION

Competition between Sumoylation and Ubiquitination of Serine Hydroxymethyltransferase 1 Determines Its Nuclear Localization and Its Accumulation in the Nucleus

(2011) Donald D. Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Localization ofde NovoThymidylate Biosynthesis Pathway Is Required to Prevent Uracil Accumulation in DNA

(2011) Amanda J. MacFarlane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel inborn error of folate metabolism: identification by exome capture and sequencing of mutations in the MTHFD1 gene in a single proband

(2011) D. Watkins et al.   JOURNAL OF MEDICAL GENETICS

Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria

(2011) D. D. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Compartmentalization of Mammalian Folate-Mediated One-Carbon Metabolism

(2010) Anne S. Tibbetts et al.   Annual Review of Nutrition

Mthfd1 is a modifier of chemically induced intestinal carcinogenesis

(2010) Amanda J. MacFarlane et al.   CARCINOGENESIS

Mthfd1Is an Essential Gene in Mice and Alters Biomarkers of Impaired One-carbon Metabolism

(2008) Amanda J. MacFarlane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reversible Compartmentalization of de Novo Purine Biosynthetic Complexes in Living Cells

(2008) S. An et al.   SCIENCE