PIKEis essential for oligodendroglia development and CNS myelination

PIKE-mediated PI3-kinase activity is required for AMPA receptor surface expression

(2011) Chi Bun Chan et al.   EMBO JOURNAL

The association of phosphoinositide 3-kinase enhancer A with hepatic insulin receptor enhances its kinase activity

(2011) Chi Bun Chan et al.   EMBO REPORTS

Proteomic identification of novel targets regulated by the mammalian target of rapamycin pathway during oligodendrocyte differentiation

(2011) William A. Tyler et al.   GLIA

Phosphoinositide 3-Kinase Enhancer Regulates Neuronal Dendritogenesis and Survival in Neocortex

(2011) C. Bun Chan et al.   JOURNAL OF NEUROSCIENCE

Levels of BDNF Impact Oligodendrocyte Lineage Cells following a Cuprizone Lesion

(2011) M. W. VonDran et al.   JOURNAL OF NEUROSCIENCE

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

(2010) Emily P. Harrington et al.   ANNALS OF NEUROLOGY

CNS-Resident Glial Progenitor/Stem Cells Produce Schwann Cells as well as Oligodendrocytes during Repair of CNS Demyelination

(2010) Malgorzata Zawadzka et al.   Cell Stem Cell

Deficiency of Phosphoinositide 3-Kinase Enhancer Protects Mice From Diet-Induced Obesity and Insulin Resistance

(2010) C. B. Chan et al.   DIABETES

Axon-oligodendrocyte interactions during developmental myelination, demyelination and repair

(2010) Gabrièle Piaton et al.   JOURNAL OF NEUROCHEMISTRY

Signals to promote myelin formation and repair

(2010) Carla Taveggia et al.   Nature Reviews Neurology

Quaking I controls a unique cytoplasmic pathway that regulates alternative splicing of myelin-associated glycoprotein

(2010) L. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oligodendrocytes: biology and pathology

(2009) Monika Bradl et al.   ACTA NEUROPATHOLOGICA

Netrin 1 and Dcc regulate oligodendrocyte process branching and membrane extension via Fyn and RhoA

(2009) S. Rajasekharan et al.   DEVELOPMENT

 1 integrins are required for normal CNS myelination and promote AKT-dependent myelin outgrowth

(2009) C. S. Barros et al.   DEVELOPMENT

Akt Signals through the Mammalian Target of Rapamycin Pathway to Regulate CNS Myelination

(2009) S. P. Narayanan et al.   JOURNAL OF NEUROSCIENCE

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

Neuroprotective Actions of PIKE-L by Inhibition of SET Proteolytic Degradation by Asparagine Endopeptidase

(2008) Zhixue Liu et al.   MOLECULAR CELL

Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B

(2008) Xiaoling Tang et al.   NATURE CELL BIOLOGY

Cdk5-mediated regulation of the PIKE-A-Akt pathway and glioblastoma cell invasion

(2008) R. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA