Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 111, Issue 29, Pages 10749-10754
Publisher
Proceedings of the National Academy of Sciences
Online
2014-07-09
DOI
10.1073/pnas.1410992111
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Inter-residue coupling contributes to high-affinity subtype-selective binding of α-bungarotoxin to nicotinic receptors
- (2013) Steven M. Sine et al. BIOCHEMICAL JOURNAL
- 50 years of allosteric interactions: the twists and turns of the models
- (2013) Jean-Pierre Changeux NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation
- (2013) L. Sauguet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PNAS Plus: From the Cover: A gating mechanism of pentameric ligand-gated ion channels
- (2013) N. Calimet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Assembly of a π–π stack of ligands in the binding site of an acetylcholine-binding protein
- (2013) Mariano Stornaiuolo et al. Nature Communications
- Structural Characterization of Binding Mode of Smoking Cessation Drugs to Nicotinic Acetylcholine Receptors through Study of Ligand Complexes with Acetylcholine-binding Protein
- (2012) Prakash Rucktooa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands
- (2012) Lars Richter et al. Nature Chemical Biology
- Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHβE Suggests a Unique Mode of Antagonism
- (2012) Azadeh Shahsavar et al. PLoS One
- Structure and Pharmacology of Pentameric Receptor Channels: From Bacteria to Brain
- (2012) Pierre-Jean Corringer et al. STRUCTURE
- Different Residues in the GABAA Receptor Benzodiazepine Binding Pocket Mediate Benzodiazepine Efficacy and Binding
- (2011) E. V. Morlock et al. MOLECULAR PHARMACOLOGY
- Principles of activation and permeation in an anion-selective Cys-loop receptor
- (2011) Ryan E. Hibbs et al. NATURE
- Crystal Structures of a Cysteine-modified Mutant in Loop D of Acetylcholine-binding Protein
- (2010) Marijke Brams et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The structural basis of function in Cys-loop receptors
- (2010) Andrew J. Thompson et al. QUARTERLY REVIEWS OF BIOPHYSICS
- Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor
- (2009) Ryan E Hibbs et al. EMBO JOURNAL
- Use of Acetylcholine Binding Protein in the Search for Novel α7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X-ray Analysis†
- (2009) Chris Ulens et al. JOURNAL OF MEDICINAL CHEMISTRY
- Nicotine binding to brain receptors requires a strong cation–π interaction
- (2009) Xinan Xiu et al. NATURE
- Cys-Loop Neuroreceptors: Structure to the Rescue?
- (2008) Dennis A. Dougherty CHEMICAL REVIEWS
- Structural Requirements for Eszopiclone and Zolpidem Binding to the γ-Aminobutyric Acid Type-A (GABAA) Receptor Are Different
- (2008) Susan M. Hanson et al. JOURNAL OF MEDICINAL CHEMISTRY
- Positive Allosteric Modulation of the 7 Nicotinic Acetylcholine Receptor: Ligand Interactions with Distinct Binding Sites and Evidence for a Prominent Role of the M2-M3 Segment
- (2008) D. Bertrand et al. MOLECULAR PHARMACOLOGY
- Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
- (2008) Ricarda J. C. Hilf et al. NATURE
- X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
- (2008) Nicolas Bocquet et al. NATURE
- X-ray structure of a prokaryotic pentameric ligand-gated ion channel
- (2008) Ricarda J. C. Hilf et al. NATURE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started