Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer
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Title
Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 110, Issue 21, Pages 8632-8637
Publisher
Proceedings of the National Academy of Sciences
Online
2013-05-09
DOI
10.1073/pnas.1305362110
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Note: Only part of the references are listed.- BRCA1 Functions Independently of Homologous Recombination in DNA Interstrand Crosslink Repair
- (2012) Samuel F. Bunting et al. MOLECULAR CELL
- Evolutionary Pathways in BRCA1-Associated Breast Tumors
- (2012) Filipe C. Martins et al. Cancer Discovery
- Mouse Models of Cancer
- (2011) Dong-Joo Cheon et al. Annual Review of Pathology-Mechanisms of Disease
- Contribution of Inherited Mutations in the BRCA2-Interacting Protein PALB2 to Familial Breast Cancer
- (2011) S. Casadei et al. CANCER RESEARCH
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- (2011) Jean-Yves Bleuyard et al. EMBO REPORTS
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- (2011) Peter Bouwman et al. JOURNAL OF PATHOLOGY
- 53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks
- (2010) Samuel F. Bunting et al. CELL
- BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells
- (2010) Gemma Molyneux et al. Cell Stem Cell
- Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice
- (2010) Pia Rantakari et al. HUMAN MOLECULAR GENETICS
- 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
- (2010) Peter Bouwman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination
- (2010) Rémi Buisson et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2
- (2010) Eloïse Dray et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- High Incidence of Protein-Truncating TP53 Mutations in BRCA1-Related Breast Cancer
- (2009) H. Holstege et al. CANCER RESEARCH
- PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response
- (2009) Feng Zhang et al. CURRENT BIOLOGY
- MRG15 Is a Novel PALB2-interacting Factor Involved in Homologous Recombination
- (2009) Shirley M.-H. Sy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Selective Requirement for 53BP1 in the Biological Response to Genomic Instability Induced by Brca1 Deficiency
- (2009) Liu Cao et al. MOLECULAR CELL
- Overexpression of RAD51 suppresses recombination defects: a possible mechanism to reverse genomic instability
- (2009) David Schild et al. NUCLEIC ACIDS RESEARCH
- X chromosome inactivation in the absence of Dicer
- (2009) C. Kanellopoulou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PALB2 is an integral component of the BRCA complex required for homologous recombination repair
- (2009) S. M. H. Sy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exomic Sequencing Identifies PALB2 as a Pancreatic Cancer Susceptibility Gene
- (2009) S. Jones et al. SCIENCE
- Analysis of FANCB and FANCN/PALB2 Fanconi Anemia genes in BRCA1/2-negative Spanish breast cancer families
- (2008) María J. García et al. BREAST CANCER RESEARCH AND TREATMENT
- Penetrance Analysis of the PALB2 c.1592delT Founder Mutation
- (2008) H. Erkko et al. CLINICAL CANCER RESEARCH
- Rad51 overexpression rescues radiation resistance in BRCA2-defective cancer cells
- (2008) Erika T. Brown et al. MOLECULAR CARCINOGENESIS
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