Systematic functional regulatory assessment of disease-associated variants

Linking disease associations with regulatory information in the human genome

(2012) M. A. Schaub et al.   GENOME RESEARCH

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Breast cancer risk–associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression

(2012) Richard Cowper-Sal·lari et al.   NATURE GENETICS

Analysis of IL12B Gene Variants in Inflammatory Bowel Disease

(2012) Jürgen Glas et al.   PLoS One

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

(2012) M. T. Maurano et al.   SCIENCE

NEW: Network-Enabled Wisdom in Biology, Medicine, and Health Care

(2012) E. E. Schadt et al.   Science Translational Medicine

Variations in Chromosomes 9 and 6p21.3 with Risk of Non-Hodgkin Lymphoma

(2011) S. S. Wang et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Potential Role of Nuclear FactorκB in Diabetic Cardiomyopathy

(2011) O. Lorenzo et al.   MEDIATORS OF INFLAMMATION

Mapping and analysis of chromatin state dynamics in nine human cell types

(2011) Jason Ernst et al.   NATURE

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

(2011) Olivier Harismendy et al.   NATURE

Charting a course for genomic medicine from base pairs to bedside

(2011) Eric D. Green et al.   NATURE

Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

(2011) Indra Adrianto et al.   NATURE GENETICS

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

Cooperative transcription factor associations discovered using regulatory variation

(2011) Konrad J. Karczewski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE

(2010) Johanna K Sandling et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Clinical assessment incorporating a personal genome

(2010) Euan A Ashley et al.   LANCET

Transcriptome genetics using second generation sequencing in a Caucasian population

(2010) Stephen B. Montgomery et al.   NATURE

Non-Synonymous and Synonymous Coding SNPs Show Similar Likelihood and Effect Size of Human Disease Association

(2010) Rong Chen et al.   PLoS One

Variation in Transcription Factor Binding Among Humans

(2010) M. Kasowski et al.   SCIENCE

The role of ghrelin and ghrelin-receptor gene variants and promoter activity in type 2 diabetes

(2009) Edwin A Garcia et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

The role of infection and inflammation in sudden infant death syndrome

(2009) Jane Blood-Siegfried   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Disease signatures are robust across tissues and experiments

(2009) Joel T Dudley et al.   Molecular Systems Biology

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polymorphisms of genes coding for ghrelin and its receptor in relation to anthropometry, circulating levels of IGF-I and IGFBP-3, and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC)

(2008) L. Dossus et al.   CARCINOGENESIS

Genetic association analyses of non-synonymous single nucleotide polymorphisms in diabetic nephropathy

(2008) D. A. Savage et al.   DIABETOLOGIA