Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited

ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia

(2012) J. H. A. Martens et al.   BLOOD

Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain

(2012) H. Jerome Coyne et al.   JOURNAL OF MOLECULAR BIOLOGY

Protein activity regulation by conformational entropy

(2012) Shiou-Ru Tzeng et al.   NATURE

Structural Basis of Ets1 Cooperative Binding to Widely Separated Sites on Promoter DNA

(2012) Nigar D. Babayeva et al.   PLoS One

Structural Modeling and DNA Binding Autoinhibition Analysis of Ergp55, a Critical Transcription Factor in Prostate Cancer

(2012) Shanti P. Gangwar et al.   PLoS One

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Genomic and Biochemical Insights into the Specificity of ETS Transcription Factors

(2011) Peter C. Hollenhorst et al.   Annual Review of Biochemistry

Promotion and maintenance of leukemia by ERG

(2011) S. Tsuzuki et al.   BLOOD

Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice

(2011) A. P. Ng et al.   BLOOD

High-pressure EPR reveals conformational equilibria and volumetric properties of spin-labeled proteins

(2011) J. McCoy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Urine TMPRSS2:ERG Fusion Transcript Stratifies Prostate Cancer Risk in Men with Elevated Serum PSA

(2011) S. A. Tomlins et al.   Science Translational Medicine

DNA Binding by the ETS Protein TEL (ETV6) Is Regulated by Autoinhibition and Self-association

(2010) Sean M. Green et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumour angiogenesis is reduced in the Tc1 mouse model of Down’s syndrome

(2010) Louise E. Reynolds et al.   NATURE

Trisomy of Erg is required for myeloproliferation in a mouse model of Down syndrome

(2009) A. P. Ng et al.   BLOOD

PU.1 Can Recruit BCL6 to DNA To Repress Gene Expression in Germinal Center B Cells

(2009) F. Wei et al.   MOLECULAR AND CELLULAR BIOLOGY

TMPRSS2-ERG and PTEN loss in prostate cancer

(2009) Jeremy A Squire   NATURE GENETICS

ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells

(2009) Y. Zong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osmolyte perturbation reveals conformational equilibria in spin-labeled proteins

(2009) Carlos J. López et al.   PROTEIN SCIENCE

The Affinity of Ets-1 for DNA is Modulated by Phosphorylation Through Transient Interactions of an Unstructured Region

(2008) Gregory M. Lee et al.   JOURNAL OF MOLECULAR BIOLOGY

The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells

(2008) Stephen J Loughran et al.   NATURE IMMUNOLOGY

A causal role for ERG in neoplastic transformation of prostate epithelium

(2008) O. Klezovitch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA