NTP-mediated nucleotide excision activity of hepatitis C virus RNA-dependent RNA polymerase

New antiviral therapies in the management of HCV infection

(2012) Harald Farnik et al.   ANTIVIRAL THERAPY

New therapies for chronic hepatitis C infection: a systematic review of evidence from clinical trials

(2012) L. Y. Lee et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Assembly, Purification, and Pre-steady-state Kinetic Analysis of Active RNA-dependent RNA Polymerase Elongation Complex

(2012) Zhinan Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNA

(2012) R. T. Mosley et al.   JOURNAL OF VIROLOGY

An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases

(2011) Marc G. Ghany et al.   HEPATOLOGY

Hepatitis C Virus Nucleotide Inhibitors PSI-352938 and PSI-353661 Exhibit a Novel Mechanism of Resistance Requiring Multiple Mutations within Replicon RNA

(2011) A. M. Lam et al.   JOURNAL OF VIROLOGY

Contribution of a mutational bias in hepatitis C virus replication to the genetic barrier in the development of drug resistance

(2011) M. H. Powdrill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of a GAG Hinge in the Nucleotide-induced Conformational Change Governing Nucleotide Specificity by T7 DNA Polymerase

(2010) Zhinan Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis of HIV-1 resistance to AZT by excision

(2010) Xiongying Tu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanism of Hepatitis C Virus RNA Polymerase Inhibition with Dihydroxypyrimidines

(2009) M. H. Powdrill et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

FitSpace Explorer: An algorithm to evaluate multidimensional parameter space in fitting kinetic data

(2008) Kenneth A. Johnson et al.   ANALYTICAL BIOCHEMISTRY

Global Kinetic Explorer: A new computer program for dynamic simulation and fitting of kinetic data

(2008) Kenneth A. Johnson et al.   ANALYTICAL BIOCHEMISTRY

Selected Replicon Variants with Low-Level In Vitro Resistance to the Hepatitis C Virus NS5B Polymerase Inhibitor PSI-6130 Lack Cross-Resistance with R1479

(2008) S. Ali et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Hepatitis C Virus Replicon Presents a Higher Barrier to Resistance to Nucleoside Analogs than to Nonnucleoside Polymerase or Protease Inhibitors

(2008) M. F. McCown et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY