Saturated and unsaturated fat induce hepatic insulin resistance independently of TLR-4 signaling and ceramide synthesis in vivo

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Diacylglycerol Activation of Protein Kinase Cε and Hepatic Insulin Resistance

(2012) François R. Jornayvaz et al.   Cell Metabolism

A Ceramide-Centric View of Insulin Resistance

(2012) Jose A. Chavez et al.   Cell Metabolism

Inflammation and Lipid Signaling in the Etiology of Insulin Resistance

(2012) Christopher K. Glass et al.   Cell Metabolism

Toll-like Receptor 4 Deficiency Promotes the Alternative Activation of Adipose Tissue Macrophages

(2012) J. S. Orr et al.   DIABETES

Intrahepatic Diacylglycerol Content Is Associated With Hepatic Insulin Resistance in Obese Subjects

(2012) Faidon Magkos et al.   GASTROENTEROLOGY

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

(2012) Durba Pal et al.   NATURE MEDICINE

Inflammation Is Necessary for Long-Term but Not Short-Term High-Fat Diet-Induced Insulin Resistance

(2011) Y. S. Lee et al.   DIABETES

SGLT2 Deletion Improves Glucose Homeostasis and Preserves Pancreatic β-Cell Function

(2011) Michael J. Jurczak et al.   DIABETES

Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-out Mice

(2011) Michael J. Jurczak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid–induced ceramide biosynthesis in mice

(2011) William L. Holland et al.   JOURNAL OF CLINICAL INVESTIGATION

Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

(2011) N. Kumashiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent advances in nonalcoholic fatty liver disease

(2010) Onpan Cheung et al.   CURRENT OPINION IN GASTROENTEROLOGY

Saturated Fatty Acids Do Not Directly Stimulate Toll-Like Receptor Signaling

(2009) Clett Erridge et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Metabolic Syndrome Pandemic

(2008) Scott M. Grundy   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Tlr-4 Deficiency Selectively Protects Against Obesity Induced by Diets High in Saturated Fat

(2008) Jeremy E. Davis et al.   Obesity