Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules

A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A

(2012) Mathew P. Martin et al.   ACS Chemical Biology

The Structural Basis for Control of Eukaryotic Protein Kinases

(2012) Jane A. Endicott et al.   Annual Review of Biochemistry

Asymmetric Stem Cell Division: Precision for Robustness

(2012) Mayu Inaba et al.   Cell Stem Cell

50 ways to build a spindle: the complexity of microtubule generation during mitosis

(2011) Tommy Duncan et al.   CHROMOSOME RESEARCH

Drosophila neuroblasts retain the daughter centrosome

(2011) Jens Januschke et al.   Nature Communications

Drug-Resistant Aurora A Mutants for Cellular Target Validation of the Small Molecule Kinase Inhibitors MLN8054 and MLN8237

(2010) Dominic A. Sloane et al.   ACS Chemical Biology

Aurora kinase inhibitors as anticancer molecules

(2010) Hiroshi Katayama et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma

(2010) G. Gorgun et al.   BLOOD

Kinetochore–microtubule interactions: steps towards bi-orientation

(2010) Tomoyuki U Tanaka   EMBO JOURNAL

HURP permits MTOC sorting for robust meiotic spindle bipolarity, similar to extra centrosome clustering in cancer cells

(2010) Manuel Breuer et al.   JOURNAL OF CELL BIOLOGY

Fast-Forwarding Hit to Lead: Aurora and Epidermal Growth Factor Receptor Kinase Inhibitor Lead Identification

(2010) Mohane Selvaraj Coumar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Regulated Degradation of Spindle Assembly Factors by the Anaphase-Promoting Complex

(2010) Ling Song et al.   MOLECULAR CELL

Identification, SAR Studies, and X-ray Co-crystallographic Analysis of a Novel Furanopyrimidine Aurora Kinase A Inhibitor

(2009) Mohane Selvaraj Coumar et al.   ChemMedChem

Spindle assembly defects leading to the formation of a monopolar mitotic apparatus

(2008) Vanessa Tillement et al.   BIOLOGY OF THE CELL

Linking Cell Cycle to Asymmetric Division: Aurora-A Phosphorylates the Par Complex to Regulate Numb Localization

(2008) Frederik Wirtz-Peitz et al.   CELL

Aurora A Regulates the Activity of HURP by Controlling the Accessibility of Its Microtubule-binding Domain

(2008) Jim Wong et al.   MOLECULAR BIOLOGY OF THE CELL