Unphosphorylated STAT5A stabilizes heterochromatin and suppresses tumor growth

CXCL5 Promotes Prostate Cancer Progression

(2015) Lesa A Begley et al.   NEOPLASIA

Targeting the Interleukin-6/Jak/Stat Pathway in Human Malignancies

(2012) Pasquale Sansone et al.   JOURNAL OF CLINICAL ONCOLOGY

Heterochromatin Formation Promotes Longevity and Represses Ribosomal RNA Synthesis

(2012) Kimberly Larson et al.   PLoS Genetics

BRCA1 tumour suppression occurs via heterochromatin-mediated silencing

(2011) Quan Zhu et al.   NATURE

Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-β and STAT3 activation

(2009) Atsushi Hosui et al.   JOURNAL OF EXPERIMENTAL MEDICINE

JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin

(2009) Mark A. Dawson et al.   NATURE

Roles of unphosphorylated STATs in signaling

(2008) Jinbo Yang et al.   CELL RESEARCH

Unphosphorylated STATs go nuclear

(2008) Stephen Brown et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Linking Heterochromatin Protein 1 (HP1) to cancer progression

(2008) George K. Dialynas et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype

(2008) Helene R. McMurray et al.   NATURE

Drosophila STAT is required for directly maintaining HP1 localization and heterochromatin stability

(2008) Song Shi et al.   NATURE CELL BIOLOGY

Canonical and non-canonical JAK–STAT signaling

(2008) Willis X. Li   TRENDS IN CELL BIOLOGY

Constitutive nuclear import of latent and activated STAT5a by its coiled coil domain

(2007) Janaki Iyer et al.   FASEB JOURNAL