Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2

Influence of the hOCT2 inhibitor cimetidine on the cellular accumulation and cytotoxicity of oxaliplatin

(2011) I. Buß et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Oxaliplatin Transport Mediated by Organic Cation/Carnitine Transporters OCTN1 and OCTN2 in Overexpressing Human Embryonic Kidney 293 Cells and Rat Dorsal Root Ganglion Neurons

(2011) N. N. Jong et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Multimodal Assessment of Painful Peripheral Neuropathy Induced by Chronic Oxaliplatin-Based Chemotherapy in Mice

(2011) Cynthia L Renn et al.   Molecular Pain

Dose Effects of Oxaliplatin on Persistent and Transient Na+ Conductances and the Development of Neurotoxicity

(2011) Susanna B. Park et al.   PLoS One

Organic Cation Transporter 2 Mediates Cisplatin-Induced Oto- and Nephrotoxicity and Is a Target for Protective Interventions

(2010) Giuliano Ciarimboli et al.   AMERICAN JOURNAL OF PATHOLOGY

Protecting Cisplatin-Induced Nephrotoxicity with Cimetidine Does Not Affect Antitumor Activity

(2010) Hiromu Katsuda et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Differential transport of platinum compounds by the human organic cation transporter hOCT2 (hSLC22A2)

(2010) H Burger et al.   BRITISH JOURNAL OF PHARMACOLOGY

Influence of Oct1/Oct2-Deficiency on Cisplatin-Induced Changes in Urinary N-Acetyl- -D-Glucosaminidase

(2010) R. M. Franke et al.   CLINICAL CANCER RESEARCH

Effect of calcium and magnesium on neurotoxicity and blood platinum concentrations in patients receiving mFOLFOX6 therapy: a prospective randomized study

(2010) Keiichiro Ishibashi et al.   International Journal of Clinical Oncology

Differential Expression of ATP7A, ATP7B and CTR1 in Adult Rat Dorsal Root Ganglion Tissue

(2010) Virginia Ip et al.   Molecular Pain

Involvement of drug transporters in the synergistic action of FOLFOX combination chemotherapy

(2009) Dirk Theile et al.   BIOCHEMICAL PHARMACOLOGY

Oxaliplatin-induced neurotoxicity: changes in axonal excitability precede development of neuropathy

(2009) Susanna B. Park et al.   BRAIN

Neuronal expression of copper transporter 1 in rat dorsal root ganglia: association with platinum neurotoxicity

(2009) Johnson J. Liu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Oral Poly(ADP-Ribose) Polymerase-1 Inhibitor BSI-401 Has Antitumor Activity and Synergizes with Oxaliplatin against Pancreatic Cancer, Preventing Acute Neurotoxicity

(2009) D. Melisi et al.   CLINICAL CANCER RESEARCH

Contribution of Organic Cation Transporter 2 (OCT2) to Cisplatin-Induced Nephrotoxicity

(2009) K K Filipski et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Acute Abnormalities of Sensory Nerve Function Associated With Oxaliplatin-Induced Neurotoxicity

(2009) Susanna B. Park et al.   JOURNAL OF CLINICAL ONCOLOGY

Platinum neurotoxicity pharmacogenetics

(2009) S. R. McWhinney et al.   MOLECULAR CANCER THERAPEUTICS

Mice with Cisplatin and Oxaliplatin-Induced Painful Neuropathy Develop Distinct Early Responses to Thermal Stimuli

(2009) Lauren E Ta et al.   Molecular Pain

Oxaliplatin-induced neuropathy in the rat: Involvement of oxalate in cold hyperalgesia but not mechanical allodynia

(2009) Mariko Sakurai et al.   PAIN

Interaction of Cisplatin with the Human Organic Cation Transporter 2

(2008) K. K. Filipski et al.   CLINICAL CANCER RESEARCH